Abstract: Disclosed is a composition for protecting nerve cells, promoting nerve cell growth and regenerating nerve cells comprising berberine, derivatives thereof or pharmaceutically acceptable salts thereof. The composition has protective effects against apoptosis of neuronal stem cells and differentiated neuronal stem cells, an effect of inducing the regeneration of nerve cells, a regenerative effect on neurites, a neuroregenerative effect on central nerves and peripheral nerves, a reformation effect on neuromuscular junctions, and a protective effect against apoptosis of nerve cells and a neuroregenerative effect in animals suffering from dementia and brain ischemia. Therefore, the composition can be used as a therapeutic agent for the prevention and treatment of neurodegenerative diseases, ischemic nervous diseases or nerve injuries, and for the improvement of learning capability.

Abstract: Disclosed is a composition for protecting nerve cells, promoting nerve cell growth and regenerating nerve cells comprising a Scutellaria Radix extract. The composition has excellent protective effects against apoptosis of neuronal stem cells and differentiated nerve cells, a positive effect of inducing the regeneration of nerve cells, a regenerative effect on neurites, a neuroregenerative effect on brain nerves and peripheral nerves, a reformation effect on neuromuscular junctions, and a protective effect agaisnt apoptosis of nerve cells and a neuroregenerative effect in animals suffering from dementia and brain ischemia. Therefore, the composition can be used as a therapeutic agent for the prevention and treatment of nerodegenerative diseases, ischemic nervous diseases or nerve injuries, and for the improvement of learning capability.