Abstract: A structured tissue belt assembly including a supporting layer and a nonwoven web contacting layer. The supporting layer has a top surface and a bottom surface and is formed of monofilaments including one or more layers of warp yarns interwoven with weft yarns in a repeating pattern. At least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns, include laser energy absorbent material, and at least one of: a) at least some of the warp yarns; or b) at least some of the weft yarns include laser energy scattering material. Laser welds attach the bottom surface of the web contacting layer to the top surface of the supporting layer at points where the web contacting layer contacts the at least one of: a) the at least some of the warp yarns; or b) the at least some of the weft yarns that include laser energy absorbent material.

Abstract: Embodiments disclosed herein include a method of patterning a substrate. In an embodiment, the method comprises, disposing a photoresist layer over a substrate, and exposing the photoresist layer to form an exposed region and an unexposed region in the photoresist layer. In an embodiment, the method further comprises treating either the exposed region or the unexposed region with a sequential infiltration synthesis (SIS) process to form a treated region, and developing the photoresist layer to remove portions of the photoresist layer other than the treated region.

Abstract: The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.

Abstract: The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.

Abstract: The disclosure relates to the field of microbial technology, in particular to a strain of Bacillus velezensis XY40-1, a fermentation method, a fermentation product and its application. The Bacillus velezensis XY40-1 was deposited in the China Center for Type Culture Collection on Mar. 29, 2022, with the deposited number of CCTCC NO: M 2022342, and was isolated from the leaves of pepper in Xiangyan Pepper Base, Changsha City, Hunan Province. The Bacillus velezensis XY40-1 and its fermentation metabolite disclosed by the disclosure have good antagonism against Geotrichum candidum, Neopestalotiopsis formicarum and Curvularia.

Abstract: Provided are printable gel or hydrogel compositions, methods of making printable gel or hydrogel compositions, uses of the printable gel or hydrogel compositions, objects formed from the printable gel or hydrogel compositions, and methods of using those objects. The printable gel or hydrogel compositions may be formed from a graphene component, a polymer component, and a carrier. The printable gel or hydrogel compositions may be used as inks in additive manufacturing techniques to 3D print a 3D object. The 3D object may be freeze-dried to form an aerogel. The aerogel may be used to remove contaminants from aqueous samples.

Abstract: A system, method, and computer program product that allows the additive manufacturing of a component from a build material held within a tank, such as the manufacture of a hydrogel biomemetic structure. The tank includes a window with a light source positioned adjacent the window. A build platform is within the tank and opposite the light source and an actuator is coupled to the build platform that movie the build platform within the tank and relative to the window. A computing device is operably coupled to the actuator and controls the operation of the actuator to build a component by positioning the build platform within the tank at predetermined distances from the window with the build platform at least partially submerged in any build material contained in the tank, and moving the build platform relative to the window and the light source thereby building a component.

Abstract: An FGF21 Fc fusion protein, a GLP-1 Fc fusion protein, and a combination therapeutic agent. The combination therapeutic agent consists of a first pharmaceutical composition comprising an FGF21 Fc fusion protein and a second pharmaceutical composition comprising a GLP-1 Fc fusion protein. The fusion proteins or a combination thereof is used for preventing or curing cardiovascular diseases and/or metabolic diseases; the diseases comprise obesity, diabetes, hyperlipidemia, nonalcoholic fatty liver disease, atherosclerosis, diabetic cardiomyopathy, coronary atherosclerotic cardiomyopathy, and other diseases related to insulin resistance.

Abstract: Methods, systems, and computer storage media for providing escorted-access management based on an escort-admin session engine are provided. The escort-admin session engine approves an external administrator's access to a resource instance based on a service team policy, while approving an escort operator to escort the external administrator in an escort-admin session that provides access to the resource. In operation, an external administrator's request for access to a resource is evaluated based on the service team policy that is managed by a service team. The request is approved with access rights to the resource identified in the policy. An escort operator is identified for the external administrator. The escort operator is approved to escort the external administrator for access to the resource during an escort-admin session. The escort-admin session includes an escort operator context referring to the escort operator having access rights based on the access rights approved using the policy.

Abstract: A fusion protein of hFGF21 or its analogs having improved pharmaceutical properties, and use of the fusion protein in preparing medicines for treating diseases, such as diabetes, obesity, non-alcoholic fatty liver disease, dyslipidemia, and/or metabolic syndrome.

Abstract: The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for an external device. When JIT access to a resource is requested by a device, the JIT service retrieves a JIT policy for the resource that includes geolocation criteria limiting the geolocation from which JIT access can be automatically granted. The geolocation of the device is evaluated against the geolocation criteria. If the geolocation criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the device.

Abstract: A method for processing network data, and a terminal, a server and a storage medium thereof are provided. The method includes: displaying a live streaming interface of a first user account logged on to the first terminal; in response to receiving a trigger instruction for the entrance, acquiring merged live streaming content and a question item; displaying the merged live streaming content and the question item on the live streaming interface; and displaying an answering result of the question item on the live streaming interface.

Abstract: Provided are resin compositions, which may be used for 3D printing. The resins may be colorless and/or transparent. The resins include a photoinitiator and one or more hard cross-linker. The resins may also include one or more of soft cross-linker(s), reactive diluent(s), filler(s), and additive(s). Also provided are articles of manufacture and methods of making articles of manufacture using one or more of the resins. The articles of manufacture may have one or more desirable mechanical and/or one or more desirable biocompatibility properties. The articles of manufacture may be colorless and/or transparent. The articles of manufacture may be produced using a method of the present disclosure.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for an external device. When JIT access to a resource is requested by a device, the JIT service retrieves a JIT policy for the resource that includes screening criteria limiting automatic granting of JIT access to users who meet the screening criteria. Screening information for a user associated with the request is evaluated against one or more screening requirements set forth by the screening criteria. If the screening criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the device.

Abstract: An apparatus and method for making a three-dimensional object from a solidifiable material using a linear solidification device is shown and described. Either a build platform or a solidification substrate has a curved surface, and each point on the curved surface traverses a trochoidal path during an object solidification operation. The curved surface allows the separation forces between the solidification substrate and the most recently solidified layer of material to be concentrated along a line instead of along a planar section which reduces the overall separation force and the likelihood of damaging a part.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for an external device. When JIT access to a resource is requested by a device, the JIT service retrieves a JIT policy for the resource that includes geolocation criteria limiting the geolocation from which JIT access can be automatically granted. The geolocation of the device is evaluated against the geolocation criteria. If the geolocation criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the device.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for an external device. When JIT access to a resource is requested by a device, the JIT service retrieves a JIT policy for the resource that includes screening criteria limiting automatic granting of JIT access to users who meet the screening criteria. Screening information for a user associated with the request is evaluated against one or more screening requirements set forth by the screening criteria. If the screening criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the device.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for DevOps personnel who do not have persistent access to restricted data or the ability to modify the cloud computing environment to gain access to restricted data. When JIT access to a resource is requested by a DevOps device, the JIT service retrieves a JIT policy for the resource that includes screening criteria limiting automatic granting of JIT access to DevOps personnel who meeting the screening criteria. Screening information for the DevOps personnel is evaluated against one or more screening requirements set forth by the screening criteria. If the screening criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the DevOps device.

Abstract: A JIT service in a cloud computing environment manages just-in-time access to resources in the cloud computing environment for DevOps personnel who do not have persistent access to restricted data or the ability to modify the cloud computing environment to gain access to restricted data. When JIT access to a resource is requested by a DevOps device, the JIT service retrieves a JIT policy for the resource that includes geolocation criteria limiting the geolocation from which JIT access can be automatically granted. The geolocation of the DevOps device is evaluated against the geolocation criteria. If the geolocation criteria and any other criteria of the JIT policy are satisfied, the JIT service provisions JIT access to the resource for the DevOps device.