Abstract: A three-dimensional cell culture platform includes a cell supporting medium having at least one microwell formed therein; and one or more microwell spacers defining an entrance of the or each microwell, the entrance enabling the introduction of a cell culture medium into the or each microwell. The volume of a microwell is determined by a surface of the one or more microwell spacers defining the entrance of the microwell, and by an interface of the cell supporting medium of the microwell. The one or more microwell spacers are in direct contact with the cell supporting medium prior to one or more cells being delivered to the three-dimensional cell culture platform.

Abstract: A method of tracking specific cells in vivo is disclosed. The method of the disclosure includes: providing fluorescent nanoparticles suitable for targeting of specific cells; administering the fluorescent nanoparticles to a subject; providing an X-ray source to irradiate the subject; and determining the distribution and growth of the specific cells by the fluorescent images from the fluorescent nanoparticles and X-ray images of the subject irradiated by the X-ray source.

Abstract: The present disclosure provides a tumor vessel embolizing agent, including: unmodified gold nanoparticles; and a pharmaceutically acceptable medium. The present disclosure also provides a method of embolizing tumor vessel, including administrating gold nanoparticles as a tumor vessel embolizing agent into a subject to accumulate the gold nanoparticles at a tumor in the subject and to embolize a vessel of the tumor.

Abstract: A method of tracking growth and metastasis of specific cells in vivo is disclosed. The method of the disclosure includes culturing the specific cells in a medium containing 0.1 ?M to 10 mM nanoparticles as a biomarker for X-rays, such that the specific cells carry the nanoparticles, administering the specific cells carrying the nanoparticles to a subject, irradiating the subject by an X-ray source, and determining the growth and metastasis of the specific cells by X-ray images of the nanoparticles in the subject.

Abstract: A method of tracking specific cells in vivo is disclosed. The method of the disclosure includes: providing fluorescent nanoparticles suitable for targeting of specific cells; administering the fluorescent nanoparticles to a subject; providing an X-ray source to irradiate the subject; and determining the distribution and growth of the specific cells by the fluorescent images from the fluorescent nanoparticles and X-ray images of the subject irradiated by the X-ray source.

Abstract: A device for transmitting light signals includes two electrode plates, a spacing structure, a cladding fluid, and a core fluid. The spacing structure, the cladding and core fluids are disposed between the electrode plates. The refractive index of the core fluid is higher than that of the cladding fluid. The core fluid is located on an electrode of one of the electrode plates, and its shape corresponds to the shape of that electrode. The shape and position is changeable and programmable by the electrodes of one of the electrode plates. The core fluid is further surrounded by the cladding fluid, forming an optical waveguide. Via these arrangements, the interface between the core and cladding fluids is much smoother than that between a fluid and a solid, so that the light signals are less likely to scatter while transmitted, in the core fluid. Therefore, the attenuation and reduction of the intensity of the light signals can be decreased. A method for transmitting light signals is also provided.

Abstract: A device for transmitting light signals includes two electrode plates, a spacing structure, a cladding fluid, and a core fluid. The spacing structure, the cladding and core fluids are disposed between the electrode plates. The refractive index of the core fluid is higher than that of the cladding fluid. The core fluid is located on an electrode of one of the electrode plates, and its shape corresponds to the shape of that electrode. The shape and position is changeable and programmable by the electrodes of one of the electrode plates. The core fluid is further surrounded by the cladding fluid, forming an optical waveguide. Via these arrangements, the interface between the core and cladding fluids is much smoother than that between a fluid and a solid, so that the light signals are less likely to scatter while transmitted, in the core fluid. Therefore, the attenuation and reduction of the intensity of the light signals can be decreased. A method for transmitting light signals is also provided.