Patents by Inventor Chia-Chi Ku

Chia-Chi Ku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MxA as an antiviral drug and as a target for identification of antiviral drugs for DNA virus infections
    Patent number: 7393941
    Abstract: The invention features methods and compositions for use in a screening assay to identify agents having antiviral activity against a DNA virus by assessing the effect of a candidate agent upon alternative splicing of MxA, or by assessing the effect of a candidate agent on production of a variant form of MxA protein. The invention also provides methods for enhancing resistance of cells to infection by a DNA virus by providing for elevated MxA and/or by providing for reduced production of variant MxA protein.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: July 1, 2008
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chia-Chi Ku, Ann M. Arvin
  • MxA as an antiviral drug and as a target for identification of antiviral drugs for DNA virus infections
    Publication number: 20070218466
    Abstract: The invention features methods and compositions for use in a screening assay to identify agents having antiviral activity against a DNA virus by assessing the effect of a candidate agent upon alternative splicing of MxA, or by assessing the effect of a candidate agent on production of a variant form of MxA protein. The invention also provides methods for enhancing resistance of cells to infection by a DNA virus by providing for elevated MxA and/or by providing for reduced production of variant MxA protein.
    Type: Application
    Filed: July 13, 2006
    Publication date: September 20, 2007
    Inventors: Chia-Chi Ku, Ann M. Arvin
  • Product and process for regulation of T cell responses
    Publication number: 20020022030
    Abstract: Disclosed is a method for increasing a memory T cell response by administering to a patient a composition that increases the activity of IL-15 and that decreases the activity of IL-2. Also disclosed is a vaccine adjuvant useful for increasing memory T cell responses. A method for inhibiting undesirable immune responses, such as autoimmune responses, is also disclosed, as is a composition useful in such a method. The composition includes a compound that increases the activity of IL-2 and in one embodiment, further includes a compound that decreases the activity of IL-15.
    Type: Application
    Filed: April 26, 2001
    Publication date: February 21, 2002
    Inventors: Philippa Marrack, John W. Kappler, Chia Chi Ku, Masaaki Murakami, Akemi Sakamoto