Abstract: A stationary trans-skull optogenetic stimulation module is provided and includes a sleeve to be inserted and positioned in a drilled hole of a skull of a subject, an optogenetic stimulating element, and a cover. The sleeve has a large aperture portion and a small aperture portion, and the optogenetic stimulating element and the cover can be installed with or disassembled from the large aperture portion. Thus, the operation time of syringe injection and phototherapeutic irradiation can be reduced, and the operation efficiency can be increased.

Abstract: A stationary trans-skull optogenetic stimulation module is provided and includes a sleeve to be inserted and positioned in a drilled hole of a skull of a subject, an optogenetic stimulating element, and a cover. The sleeve has a large aperture portion and a small aperture portion, and the optogenetic stimulating element and the cover can be installed with or disassembled from the large aperture portion. Thus, the operation time of syringe injection and phototherapeutic irradiation can be reduced, and the operation efficiency can be increased.

Abstract: A skull endosseous module for ultrasound penetration is provided and includes a fixation sleeve permanently inserted and positioned in a drilled hole of a skull, a movable sleeve movably inserted in the fixation sleeve for providing a hollow ultrasound guiding channel; and an outer cover mounted on an outer opening of the fixation sleeve and covered by a scalp tissue. Thus, an ultrasound device outside the scalp tissue can generate ultrasounds to pass through the outer cover and the ultrasound guiding channel for affecting a target region of a brain tissue in the skull.

Abstract: A skull endosseous module for ultrasound penetration is provided and includes a fixation sleeve permanently inserted and positioned in a drilled hole of a skull, a movable sleeve movably inserted in the fixation sleeve for providing a hollow ultrasound guiding channel; and an outer cover mounted on an outer opening of the fixation sleeve and covered by a scalp tissue. Thus, an ultrasound device outside the scalp tissue can generate ultrasounds to pass through the outer cover and the ultrasound guiding channel for affecting a target region of a brain tissue in the skull.

Abstract: Disclosed is a skull endosseous implant adapted to be implanted in the subject's skull to provide an access channel. A variety of sensor means may be installed in the access channel for monitoring the intracranial status of the subject. The present invention further provides a kit containing the skull endosseous implant.

Abstract: Disclosed is a skull endosseous implant adapted to be implanted in the subject's skull to provide an access channel. A variety of sensor means may be installed in the access channel for monitoring the intracranial status of the subject. The present invention further provides a kit containing the skull endosseous implant.