Abstract: The title compounds are provided as well as a method for their production, pharmaceutical compositions comprising the compounds, and a method of treatment using the compounds in dosage form. Compounds of the invention have pharmacological properties and are useful antimicrobial agents and antileukemic agents.

Abstract: An antineoplastic 1,4-bis-substituted-9-10-anthracenedione having the formula ##STR1## wherein W, X, Y and Z are each independently selected from the group consisting of hydrogen, OH, NH.sub.2, OCH.sub.3, N(CH.sub.3).sub.2, F, Cl, Br, I, alkyl groups containing from 1-8 carbon atoms, glucosides, phenyl and substituted phenyl, and R is selected from the group consisting of alkyl amino groups containing from 1-8 carbon atoms, alkylaminoalkyl groups containing from 1-8 carbon atoms, substituted alkylamino-alkyl groups containing from 1-8 carbon atoms, and substituted aminoaryl groups.

Abstract: 5,6-Dihydro-6-alkoxynitidine compounds of the formula ##STR1## wherein R.sub.1 and R.sub. 2 are selected independently from the group consisting of C.sub.1 -C.sub.6 alkyl groups, H and benzyl or R.sub.1 and R.sub.2 taken together are methylene and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are selected independently from the group consisting of C.sub.1 -C.sub.6 alkyl groups, H and benzyl are anti-leukemic agents.