Abstract: The invention surprisingly found that agents that inhibit system xc? provide the therapeutic intervention in substance-related and addictive disorders and the treatment and/or prevention in substance-mediated brain damage and confirms that system xc? is a promising therapeutic target for substance-induced addiction and brain damage.

Abstract: A method for enhancing an insulin like growth factor 1 receptor expression of a mesenchymal stem cell is provided. The method includes culturing a plurality of mesenchymal stem cells expressing insulin-like growth factor 1 receptors in media containing human cord blood serum to enhance the insulin like growth factor 1 receptor expression of the mesenchymal stem cells.

Abstract: Moving an article after a material, such as a hot-melt adhesive, has been applied to a surface of the article is accomplished with an article transfer apparatus. The apparatus is comprised of a belt having a plurality of apertures extending there through that are effective to communicate a vacuum pressure from an inner surface of the belt to a contacting surface of the belt. The vacuum pressure secures and adheres the article to the contacting surface of the belt as the belt conveys the article. The vacuum pressure is distributed along the inner surface of the belt by a vacuum chamber, which is between a compression roller and a second roller.

Abstract: Moving an article after a material, such as a hot-melt adhesive, has been applied to a surface of the article is accomplished with an article transfer apparatus. The apparatus is comprised of a belt having a plurality of apertures extending there through that are effective to communicate a vacuum pressure from an inner surface of the belt to a contacting surface of the belt. The vacuum pressure secures and adheres the article to the contacting surface of the belt as the belt conveys the article. The vacuum pressure is distributed along the inner surface of the belt by a vacuum chamber, which is between a compression roller and a second roller.

Abstract: A mesenchymal stem cell is provided. The mesenchymal stem cell that expresses an insulin-like growth factor 1 receptor have been cultured in media containing human cord blood serum and isolated, such that an insulin-like growth factor 1 receptor expression is enhanced in the isolated mesenchymal stem cells.

Abstract: A whistle capable of detecting an air pressure includes a housing and a circuit board module. The housing further includes a shell body and a division assembly. The shell body has an interior space. The division assembly dividing the interior space into an air chamber and an accommodation chamber further has a detection opening communicative in space with the air chamber. The air chamber has a blow hole for a user to blow an air into the air chamber. The circuit board module located in the shell body includes a main board and an air-pressure sensor. The main board partly at least located in the accommodation chamber has an air-detecting region respective to the detection opening The air-pressure sensor mounted in the air-detecting region is to detect the air and to transmit a corresponding detection signal upon detecting the air.

Abstract: Methods of treating brain ischema or hypoxia by using an inhibitor of cysteine-glutamate transporter (i.e. system xc?) is provided. The inhibitor includes sorafenib and a derivative thereof, erastin, and suifasalazine. These inhibitors can effectively decrease a concentration of extracellular glutamate, so that excitotoxicity to central nervous system (CNS) and a cortical infarct volume in brains can be reduced.

Abstract: Moving an article after a material, such as a hot-melt adhesive, has been applied to a surface of the article is accomplished with an article transfer apparatus. The apparatus is comprised of a belt having a plurality of apertures extending there through that are effective to communicate a vacuum pressure from an inner surface of the belt to a contacting surface of the belt. The vacuum pressure secures and adheres the article to the contacting surface of the belt as the belt conveys the article. The vacuum pressure is distributed along the inner surface of the belt by a vacuum chamber, which is between a compression roller and a second roller.

Abstract: A packaging method for forming a conduction cooled package (CCP) laser is provided and includes soldering a semiconductor laser device on the first heat spreader; and then bonding the first heat spreader on the second spreader via an Al/Ni nano-laminated foil. Moreover, a CCP laser is also provided herein.

Abstract: A blender includes a container mounted removably on a housing for containing food items and provided with a cutting blade unit that is to be driven rotatably by a motor unit when the container is mounted on the housing. A control unit is operable in accordance with an initial control signal from a switch unit so as to activate the motor unit to operate in a judgment mode. The control unit determines food processing conditions in accordance with a motor rotation signal generated by a sensor unit for indicating a rotary speed of the motor unit when the motor unit is operated in the judgment mode. The control unit switches operation of the motor unit from the judgment mode to a food processing mode upon determining the food processing conditions so as to drive rotation of the cutting blade unit to blend the food items contained in the container.

Abstract: A blender includes a container mounted removably on a housing for containing food items and provided with a cutting blade unit that is to be driven rotatably by a motor unit when the container is mounted on the housing. A control unit is operable in accordance with an initial control signal from a switch unit so as to activate the motor unit to operate in a judgment mode. The control unit determines food processing conditions in accordance with a motor rotation signal generated by a sensor unit for indicating a rotary speed of the motor unit when the motor unit is operated in the judgment mode. The control unit switches operation of the motor unit from the judgment mode to a food processing mode upon determining the food processing conditions so as to drive rotation of the cutting blade unit to blend the food items contained in the container.

Abstract: A built-in back-up power device operates a high-power apparatus for a short time period to prevent the loss of data or damage to the apparatus when power from a utility power source is interrupted. The built-in back-up power device includes a battery and a charger. The charger charges the battery when power is provided from the utility power source. During a power interruption or outage, the battery outputs back-up power to the high-power apparatus. A computer with such a built-in back-up power device is also provided.