Patents by Inventor Chia-Hung Lee

Chia-Hung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8734844
    Abstract: A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle; b) providing a solution comprising Au+3 ions; c) suspending the amine-modified silica particle in the solution comprising Au+3 ions; d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle; e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications; and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs).
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: May 27, 2014
    Assignee: National Health Research Institutes
    Inventors: Chia-Hung Lee, Wei-Neng Liao, Shih-Hsun Cheng, Jen-Kun Chen, Chung-Shi Yang, Leu-Wei Lo, Yeu-Kuang Hwu, Fong-Sian Lin
  • Patent number: 8559280
    Abstract: The invention provides a method for data recording of an optical disk drive. First, raw data is encoded to obtain a plurality of recording units of encoded data to be stored in a memory. The encoded data stored in the memory is then recorded to an optical disk. A predetermined number of recording units of the encoded data is then reserved in the memory as reserved data without being recorded onto the optical disk. The recorded data read from the optical disk is then compared to the corresponding encoded data stored in the memory to verify correctness of the recorded data. The reserved data is then recorded to the optical disk after correctness verification of the recorded data is completed. Finally, the aforementioned steps are repeated until there is no more raw data left as a source for encoding.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: October 15, 2013
    Assignee: Mediatek Inc.
    Inventors: Hsin-Cheng Chen, Chao-Yi Wu, Chia-Hung Lee, Yao-Chun Fang
  • Patent number: 8348210
    Abstract: A positioning device for shelves includes a support and a sleeve, the support has a first end and a second end. A tail board extends from the first end and a notch is defined in the tail board. The sleeve has a passage defined axially therethrough and at least one stop extends inward from the inner periphery of the passage. The tail board is inserted into the passage and the stop is engaged with the notch so as to secure the support to the passage. An engaging portion is located in the notch and located corresponding to the stop.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: January 8, 2013
    Inventor: Chia-Hung Lee
  • Patent number: 8252337
    Abstract: A charged mesoporous silica nanoparticle (MSN)-based drug delivery system for controlled release and enhanced bioavailability is disclosed. The system comprises a positively charged MSN, which has a silica matrix and an array of pores and/or nanochannels in the matrix. The entire substance of the matrix, all the surfaces and the pores and/or nanochannels comprise a plurality of silanol (Si—OH) and quaternary ammonium functional groups. The bioavailability of a negatively charged bioactive compound can be increased by loading it into the pores and/or nanochannels. The silanol (Si—OH) functional groups on the surfaces lining the walls of the pores and/or nanochannels are free to deprotonate in a fluid having pH above the pI of the positively charged MSN and lead to a sustained release of the negatively charged drug from the pores and/or nanochannels, and thereby enhance the bioavailability of the drug.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: August 28, 2012
    Assignee: National Health Research Institutes
    Inventors: Chia-Hung Lee, Leu-Wei Lo, Chung-Shi Yang, Chung-Yuan Mou
  • Publication number: 20120130053
    Abstract: A method of synthesizing ligand-conjugated gold nanoparticles (AuNPs) is disclosed. The method comprises: a) providing an amine-modified silica particle; b) providing a solution comprising Au+3 ions; c) suspending the amine-modified silica particle in the solution comprising Au+3 ions; d) allowing the Au3+ ions to be adsorbed and/or immobilized onto the surface of the amine-modified silica particle; e) exposing the Au3+ ions immobilized onto the surface of the amine-modified silica particle to radiation to obtain bare gold nanoparticles (AuNPs) adsorbed and/or immobilized onto the surface of the amine-modified silica particle, wherein the bare AuNPs are without organic surface modifications; and f) reacting a ligand with the bare AuNPs adsorbed and/or immobilized onto the surface of the amine-modified SiNP and thereby obtain ligand-conjugated gold nanoparticles (AuNPs).
    Type: Application
    Filed: May 17, 2011
    Publication date: May 24, 2012
    Applicant: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: CHIA-HUNG LEE, WEI-NENG LIAO, SHIH-HSUN CHENG, JEN-KUN CHEN, CHUNG-SHI YANG, LEU-WEI LO, YEU-KUANG HWU, FONG-SIAN LIN
  • Patent number: 8009531
    Abstract: A method of recording data onto an optical storage medium includes: before starting recording data onto the optical storage medium from an expected link point on the optical storage medium, setting a current recording condition corresponding to the expected link point according to at least one previous recording condition corresponding to the expected link point; and controlling an operation of recording the data onto the optical storage medium according to the current recording condition.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: August 30, 2011
    Assignee: Mediatek Inc.
    Inventors: Chia-Hung Lee, Chao-Ming Huang, Jui-Hung Yen
  • Patent number: 7958625
    Abstract: An assembly device includes a base having a supporting portion upon which an isolation cover and a main body are disposed. A press-fitting mechanism is movably connected to the base, and includes a press-fitting portion facing the supporting portion and disposed corresponding in position to the supporting portion, and further portions for guiding and bending second positioning portions. The further portions are movably disposed on external side faces of the press-fitting portion. The press-fitting mechanism also has first portions for holding the further portions to the external side faces of the press-fitting portion, and has second portions passing through upper ends of the further portions. A drive mechanism is disposed at the base and has a drive portion connected to the press-fitting mechanism, for driving the press-fitting mechanism to move towards the supporting portion via the drive portion, so as to bend and fasten ends of second positioning portions.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: June 14, 2011
    Assignee: Askey Computer Corp.
    Inventors: Chia-Hung Lee, Jen-Huan Yu, Chung-Shao Huang, Ching-Feng Hsieh, Cheng-Wen Dai, Kuo-Ching Chen
  • Publication number: 20110080813
    Abstract: A method of recording data onto an optical storage medium includes: before starting recording data onto the optical storage medium from an expected link point on the optical storage medium, setting a current recording condition corresponding to the expected link point according to at least one previous recording condition corresponding to the expected link point; and controlling an operation of recording the data onto the optical storage medium according to the current recording condition.
    Type: Application
    Filed: October 1, 2009
    Publication date: April 7, 2011
    Inventors: Chia-Hung Lee, Chao-Ming Huang, Jui-Hung Yen
  • Publication number: 20100104650
    Abstract: A charged mesoporous silica nanoparticle (MSN)-based drug delivery system for controlled release and enhanced bioavailability is disclosed. The system comprises a positively charged MSN, which has a silica matrix and an array of pores and/or nanochannels in the matrix. The entire substance of the matrix, all the surfaces and the pores and/or nanochannels comprise a plurality of silanol (Si—OH) and quaternary ammonium functional groups. The bioavailability of a negatively charged bioactive compound can be increased by loading it into the pores and/or nanochannels. The silanol (Si—OH) functional groups on the surfaces lining the walls of the pores and/or nanochannels are free to deprotonate in a fluid having pH above the pI of the positively charged MSN and lead to a sustained release of the negatively charged drug from the pores and/or nanochannels, and thereby enhance the bioavailability of the drug.
    Type: Application
    Filed: October 20, 2009
    Publication date: April 29, 2010
    Applicant: National Health Research Insitutue
    Inventors: Chia-Hung Lee, Leu-Wei Lo, Chung-Shi Yang, Chung-Yuan Mou
  • Publication number: 20100095518
    Abstract: An assembly device applicable to assembling an isolation cover to a main body of a circuit board is provided. The main body and the isolation cover respectively have a plurality of first positioning portions and a plurality of second positioning portions corresponding to each other. The second positioning portions correspondingly pass through the first positioning portions, respectively. The assembly device includes a base, a press-fitting mechanism movably connected to the base, and a drive mechanism disposed at the base. The base has a supporting portion for disposing the isolation cover and the main body. The press-fitting mechanism has a press-fitting portion facing the supporting portion. The drive mechanism has a drive portion connected to the press-fitting mechanism, for driving the press-fitting mechanism to move towards the supporting portion of the base via the drive portion, so as to bend and fasten ends of the second positioning portions.
    Type: Application
    Filed: February 5, 2009
    Publication date: April 22, 2010
    Applicant: ASKEY COMPUTER CORP.
    Inventors: Chia-Hung LEE, Jen-Huan YU, Chung-Shao HUANG, Ching-Feng HSIEH, Cheng-Wen DAI, Kuo-Ching CHEN
  • Publication number: 20090323487
    Abstract: The invention provides a method for data recording of an optical disk drive. First, raw data is encoded to obtain a plurality of recording units of encoded data to be stored in a memory. The encoded data stored in the memory is then recorded to an optical disk. A predetermined number of recording units of the encoded data is then reserved in the memory as reserved data without being recorded onto the optical disk. The recorded data read from the optical disk is then compared to the corresponding encoded data stored in the memory to verify correctness of the recorded data. The reserved data is then recorded to the optical disk after correctness verification of the recorded data is completed. Finally, the aforementioned steps are repeated until there is no more raw data left as a source for encoding.
    Type: Application
    Filed: March 30, 2009
    Publication date: December 31, 2009
    Applicant: MEDIATEK INC.
    Inventors: Hsin-Cheng Chen, Chao-Yi Wu, Chia-Hung Lee, Yao-Chun Fang