Abstract: A method for treating a disease caused by protein retention in the endoplasmic reticulum (ER) with a sarcoplasmic/endoplasmic reticulum calcium ATPase pump inhibitor encapsulated in a polymer nanoparticle. The polymer nanoparticle is surface-modified such that it is targeted to the ER. The inhibitor reduces protein retention in the ER and the encapsulation lowers side effects of the inhibitor, e.g., cytotoxicity, as compared to administering the inhibitor without encapsulation. Also disclosed is a pharmaceutical composition that can be used for carrying out the method. Further provided is a transgenic mouse carrying in its genome a heterologous nucleic acid that encodes an H338Y mutant gp91phox protein. The transgenic mouse can serve as a model for human chronic granulomatous disease.

Abstract: A method for treating a disease caused by protein retention in the endoplasmic reticulum (ER) with a sarcoplasmic/endoplasmic reticulum calcium ATPase pump inhibitor encapsulated in a polymer nanoparticle. The polymer nanoparticle is surface-modified such that it is targeted to the ER. The inhibitor reduces protein retention in the ER and the encapsulation lowers side effects of the inhibitor, e.g., cytotoxicity, as compared to administering the inhibitor without encapsulation. Also disclosed is a pharmaceutical composition that can be used for carrying out the method. Further provided is a transgenic mouse carrying in its genome a heterologous nucleic acid that encodes an H338Y mutant gp91phox protein. The transgenic mouse can serve as a model for human chronic granulomatous disease.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A positioning unit is mounted on an electronic device and includes a catch member and a locking member. The catch member defines a gap which has a width that is reducible when the catch member moves from a non-catching position to a catching position and that is expandable when the catch member moves from the catching position to the non-catching position. The locking member has an engaging end extending into the gap. The locking member is operable to move the catch member from the non-catching position to the catching position and from the catching position to an urging position. The engaging end of the locking member engages the catch member when the width of the gap is reduced upon movement of the catch member to the catching position. The engaging end of the locking member disengages from the catch member when the width of the gap is enlarged upon movement of the catch member to the non-catching position.

Abstract: A data processing device includes a main body, a display unit, a keyboard unit, and a liquid discharge path. The main body includes a casing and a circuit board. The casing includes an upper case having a top side formed with a tray receiving recess that is confined by an upright peripheral wall. The display and keyboard units are coupled electrically to the main body. The keyboard unit includes a tray and a plurality of keys. The tray includes a bottom wall and a surrounding wall. The liquid discharge path is formed through the surrounding wall and the peripheral wall, and/or through the bottom wall of the tray and the upper and lower cases of the casing, and is adapted to permit discharge of liquid that spills into the tray.

Abstract: A positioning unit is mounted on an electronic device and includes a catch member and a locking member. The catch member defines a gap which has a width that is reducible when the catch member moves from a non-catching position to a catching position and that is expandable when the catch member moves from the catching position to the non-catching position. The locking member has an engaging end extending into the gap. The locking member is operable to move the catch member from the non-catching position to the catching position and from the catching position to an urging position. The engaging end of the locking member engages the catch member when the width of the gap is reduced upon movement of the catch member to the catching position. The engaging end of the locking member disengages from the catch member when the width of the gap is enlarged upon movement of the catch member to the non-catching position.

Abstract: A data processing device includes a main body, a display unit, a keyboard unit, and a liquid discharge path. The main body includes a casing and a circuit board. The casing includes an upper case having a top side formed with a tray receiving recess that is confined by an upright peripheral wall. The display and keyboard units are coupled electrically to the main body. The keyboard unit includes a tray and a plurality of keys. The tray includes a bottom wall and a surrounding wall. The liquid discharge path is formed through the surrounding wall and the peripheral wall, and/or through the bottom wall of the tray and the upper and lower cases of the casing, and is adapted to permit discharge of liquid that spills into the tray.

Abstract: A latch unit is mounted on an electronic device having first and second housings. The latch unit includes a hook member for interlocking the first and second housings. The hook member is mounted in the first housing and has opposite first and second engaging ends. The first engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to an engaging position when the first housing is positioned at a first transverse position. The second engaging end projects from the first housing and extends into and releasably engages the second housing upon movement of the hook member to the engaging position when the first housing is positioned at a second transverse position.

Abstract: A position unit is mounted on an electronic device and includes a catch member and a locking member. The catch member defines a gap which has a width that is reducible when the catch member moves from a non-catching position to a catching position and that is expandable when the catch member moves from the catching position to the non-catching position. The locking member has an engine end extending into the gap. The locking member is operable to move the catch member from the non-catching position to the catching position and from the catching position to an urging position. The engaging end of the locking member engages the catch member when the width of the gap is reduced upon movement of the catch member to the catching position. The engaging end of the locking member disengages from the catch member when the width of the gap is enlarged upon movement of the catch member to the non-catching position.