Patents by Inventor Chia-Lin Jeff Wang

Chia-Lin Jeff Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,2,3,4-tetrahydroisoquinoline derivatives and pharmaceutical composition thereof
    Patent number: 5756516
    Abstract: The invention relates to compounds of formula (I) ##STR1## wherein R.sup.1 is an optional substituent any position of phenyl ring and is selected from halogen, --NO.sub.2, --NH.sub.2, --OH and --O--CR.sub.1-6 alkyl;--CH.sub.2 R.sup.2 is a substituent at 1- or 3- position of 1,2,3,4-tetrahydroisoquinoline, whereinR.sup.2 is an azole group such as imidazole or triazole; andR.sup.3 is phenyl optionally substituted with one or more halogen,and pharmaceutical salts thereof.The compounds of formula (I) and salts thereof are useful as antifungal agents.The invention also relates to the antifungal pharmaceutical compositions containing the compounds of formula (I), the methods of treating fungal infections using the compounds of formula (I) and the process for preparing the compounds of formula (I).
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: May 26, 1998
    Assignee: Development Center for Biotechnology
    Inventors: Lee-Tai Liu, Mei-Shey Lin, Ya-Chuan Lin, Su-Chen Yen, Hsiao-Jen Chen, Hsiang-Ling Huang, Chia-Lin Jeff Wang