Patents by Inventor Chia Soo

Chia Soo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for inducing human pluripotent stem cells
    Patent number: 10190097
    Abstract: The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises steps of treating a human cell with a cell culture medium comprising fibromodulin (FMOD) for a period ranging from a day to a month, and changing the cell culture medium regularly until a FMOD reprogrammed (FreP) cell forms; wherein the FreP cell expresses NANOG and does not form teratoma, and wherein the human cell is a fibroblastic cell.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: January 29, 2019
    Assignee: The Regents of the University of California
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • ISOFORM NELL-1 PEPTIDE
    Publication number: 20180236029
    Abstract: This application is drawn to a method of using an isoform NELL-1 peptide, and compositions thereof for bone formation or for treating, preventing, or ameliorating osteoporosis.
    Type: Application
    Filed: April 16, 2018
    Publication date: August 23, 2018
    Inventors: Kang TING, B. Chia SOO
  • Fibromodulin formulation for reducing corneal scarring
    Patent number: 10016452
    Abstract: A formulation for reducing corneal scarring and related eye conditions, is disclosed. The formulation comprises an effective amount of fibromodulin and can be administered intraocularly, such as by topical application, injection into the eye, or implantation in or on the eye.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: July 10, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Chia Soo
  • Isoform nell-1 peptide
    Patent number: 9974828
    Abstract: This application is drawn to a method of using an isoform NELL-1 peptide, and compositions thereof for bone formation or for treating, preventing, or ameliorating osteoporosis.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: May 22, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kang Ting, Chia Soo
  • Re-conditioned serum-free culture medium composition obtained by culturing mammalian cells in Fibromodulin
    Patent number: 9885014
    Abstract: The present invention provides pluripotent stem cell like (PSCL) cells or clones, a culture medium therefore, and a supernatant thereof, and methods of making and using the same.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: February 6, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kang Ting, B. Chia Soo, Zhong Zheng
  • METHODS AND COMPOSITIONS FOR MODULATING MYOFIBROBLAST ACTIVITIES
    Publication number: 20170333528
    Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG
  • NOVEL WOUND-HEALING-ENHANCING DEVICES
    Publication number: 20170312393
    Abstract: Provided herein is a wound-healing-enhancing device that comprises a body structure and a wound-healing-enhancing agent in a wound-healing-enhancing effective amount. Methods of fabricating and using the device are also provided.
    Type: Application
    Filed: June 8, 2017
    Publication date: November 2, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG, Benjamin M. WU, Yulong ZHANG
  • Methods and compositions using compounds from fetal cells and tissues to improve condition of skin
    Patent number: 9782337
    Abstract: Compositions comprising one or more compounds expressed by fetal tissues for modulating skin conditions, methods of identifying the compounds, and methods of making and using the compounds are provided.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 10, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Chia Soo
  • METHODS OF PROMOTING TISSUE HEALING AND REPAIR
    Publication number: 20170266256
    Abstract: Provided herein is a method of promoting tissue repair, comprising delivering to a subject a therapeutically effective amount of fibromodulin (FMOD), FMOD polypeptide, FMOD peptide, or a variant or derivative or analog thereof according to a dosing regimen to cause an injured tissue to form a repaired tissue having an improved condition provided that the improved condition does not include improved condition of scar of skin.
    Type: Application
    Filed: June 8, 2017
    Publication date: September 21, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG
  • Methods and compositions for modulating myofibroblast activities
    Patent number: 9744214
    Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: August 29, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Perivascular stem cell composition for bone
    Patent number: 9730965
    Abstract: Embodiments of the present invention provide an osteogenic composition comprising perivascular stem cells or induced pluripotent cells (iPS) and an osteogenic agent and methods of making and using the same.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: August 15, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: B. Chia Soo, Kang Ting, Bruno Peault
  • RECOMBINANT NEL-LIKE (NELL) PROTEIN PRODUCTION
    Publication number: 20170190756
    Abstract: The present invention provides a method and system for producing a NELL protein. The method and system comprise a CELL encoding a NELL protein or peptide and a non-insect secretory signal peptide.
    Type: Application
    Filed: March 17, 2017
    Publication date: July 6, 2017
    Inventors: Kang TING, Chia SOO
  • WOUND-HEALING-ENHANCING DEVICES
    Publication number: 20170182207
    Abstract: Provided herein is a biocompatible device comprising a body structure and a wound-healing-enhancing agent in a wound-healing-enhancing effective amount, wherein the wound-healing-enhancing agent is embedded within the body structure or coated on the body structure. An example of the device is a surgical suture. Methods of fabricating and using the device are also provided.
    Type: Application
    Filed: December 9, 2016
    Publication date: June 29, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong ZHENG, Benjamin M. WU, Yulong ZHANG
  • PHARMACEUTICAL COMPOSITIONS FOR TREATING OR PREVENTING BONE CONDITIONS
    Publication number: 20170165323
    Abstract: Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 15, 2017
    Inventors: Chia SOO, Kang TING, Shunichi KURODA, Ben WOO
  • METHOD AND COMPOSITION FOR INDUCING HUMAN PLURIPOTENT STEM CELLS
    Publication number: 20170159021
    Abstract: The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell. This application includes the sequence listing which is identical to the sequence information in the last filed computer readable form (CFR) on Aug. 1, 2014 in U.S. application Ser. No. 14/353,284, filed Apr. 21, 2014, entitled “2014-08-01 384578-991391 ST25.tax” and is hereby incorporated by reference in its entirety.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 8, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong Zheng
  • METHOD AND COMPOSITION FOR INDUCING HUMAN PLURIPOTENT STEM CELLS
    Publication number: 20170159022
    Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell.
    Type: Application
    Filed: December 19, 2016
    Publication date: June 8, 2017
    Inventors: B. Chia SOO, Kang TING, Zhong Zheng
  • Recombinant NEL-like (NELL) protein production
    Patent number: 9598480
    Abstract: The present invention provides a method and system for producing a NELL protein. The method and system comprise a CELL encoding a NELL protein or peptide and a non-insect secretory signal peptide.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: March 21, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kang Ting, Chia Soo
  • ISOFORM NELL-1 PEPTIDE
    Publication number: 20170042968
    Abstract: This application is drawn to a method of using an isoform NELL-1 peptide, and compositions thereof for bone formation or for treating, preventing, or ameliorating osteoporosis.
    Type: Application
    Filed: September 14, 2016
    Publication date: February 16, 2017
    Inventors: Kang Ting, Chia Soo
  • Method and composition for inducing human pluripotent stem cells
    Patent number: 9549954
    Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: January 24, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: B. Chia Soo, Kang Ting, Zhong Zheng
  • Pharmaceutical compositions for treating or preventing bone conditions
    Patent number: 9511115
    Abstract: Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: December 6, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Chia Soo, Kang Ting, Shunichi Kuroda, Ben Wu