Abstract: Provided herein are methods of treating or preventing a T-cell mediated inflammatory disease or cancer in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antibody that specifically binds to human PSGL-1 in combination with a Janus kinase (JAK) inhibitor. In some embodiments, the T-cell mediated inflammatory disease is GVHD, e.g., acute GVHD or chronic GVHD.

Abstract: Electrodes that can be used to determine a first type of physiological signal and a second type of physiological signal are disclosed. The first type of physiological signal can be electromyography (EMG) signals produced by activity of muscles and tendons. Identification of hand movements can be supplemented with pose detection circuitry such as inertial measurement units (IMUs). These EMG signals can be processed to identify hand movements and recognize gestures associated with those hand movements. The second type of physiological signal can be electromyography (ECG) signals produced by the heart. The electrodes can be used to detect EMG and ECG signals dependent upon a current configuration of sensing circuitry. The electrodes can be used to determine a measurement quality associated with the EMG signals.

Abstract: A chip provided to be flip bonded to a circuit board includes at least one bump and at least one supportive element which protrudes from an active surface of the chip and is located between the bump and a first side of the active surface. The supportive element is provided to support a lead on the circuit board to prevent the lead from contacting a metal burr protruding from the active surface or a metal cut surface exposed on a side wall of the chip. The supportive element can protect the chip and the lead from short circuit or electrical abnormality.

Abstract: A semiconductor package includes a flexible circuit board and a chip which includes a first bump group and a second bump group. First bumps of the first bump group and second bumps of the second bump group are provided to be bonded to leads on the flexible circuit board. The second bumps are designed to be longer than the first bumps in length so as to increase bonding strength of the second bumps to the leads, prevent the leads from being shifted and separated from the first and second bumps and prevent lead bonding misalignment.

Abstract: An automated optical inspection method, an automated optical inspection system, and a storage medium are provided. The method includes the following. An original image including first images of a target object is captured by an optical lens. An edge detection is performed on the original image to obtain an edge image including second images having an edge pattern. At least one of maximum, minimum, and average values of a pixel value in the second images is calculated. The edge image is divided into image blocks according to a unit area, and characteristic values are calculated according to the at least one of the maximum, minimum, and average values corresponding to the second images included in the image blocks. An optimal regression model is obtained by training a regression model corresponding to a defect of the target object according to the characteristic values and a data of the target object.

Abstract: A composite quantum-dot optical film comprises a quantum-dot layer and a substrate, wherein the substrate comprises a unitary body formed by a first material, wherein a plurality of particles are disposed in the unitary body that encapsulates an outer surface of a first particle with said outer surface of the first particle being located above the top surface of the unitary body, wherein the substrate is disposed over the quantum-dot layer.

Abstract: The present invention discloses a quantum-dot composite optical film comprising: a plurality of quantum dots dispersed in the optical film, wherein the plurality of quantum dots are capable of being water-resistant and oxygen-resistant; and a plurality of prisms, disposed over the quantum-dot layer.

Abstract: An electronic device such as a wristwatch may be provided with conductive structures. The conductive structures may include a sensor electrode for an electrocardiogram (ECG) sensor. A coating may be disposed on the sensor electrode to reflect particular wavelengths of visible light so that the sensor electrode exhibits a desired color. The coating may include adhesion and transition layers on the sensor electrode, an opaque coloring layer on the adhesion and transition layers, and a thin-film interference filter on the opaque coloring layer. The thin-film interference filter may have an uppermost diamond-like carbon (DLC) layer. The DLC layer may contribute to the color response of the coating while concurrently minimizing noise in ECG waveforms gathered by the ECG sensor using the sensor electrode.

Abstract: The present disclosure provides a method of manufacturing a semiconductor device. The method includes: forming a transistor region in a substrate; forming a gate dielectric layer over the transistor region; forming a diffusion-blocking layer over the gate dielectric layer; forming a first portion of a work function layer over the diffusion-blocking layer; forming a second portion of the work function layer over the first portion of the work function layer; forming a plurality of barrier elements on or under a top surface of the second portion of the work function layer; and forming a gate electrode over the work function layer, wherein the plurality of barrier elements block oxygen from diffusing into the work function layer during the formation of the gate electrode.

Abstract: The present invention discloses a quantum-dot film, wherein the quantum-dot film comprises a binder and a plurality of quantum dots dispersed in the binder, wherein the plurality of quantum dots are capable of being water-resistant and oxygen-resistant.

Abstract: An optical structure, comprising an optical film having a substrate, wherein a first plurality of multi-faceted recesses are formed on the top surface of the substrate, wherein a prism module is disposed over the first optical film, wherein the prism module comprises a plurality of prism sheets that are stacked and bonded to each other.

Abstract: An optical film, comprising a substrate, wherein a first plurality of multi-faceted recesses are formed on the substrate, wherein the plurality of multi-faceted recesses are capable of scattering lights that enter into a second surface of the substrate, said first surface and said second surface are two opposite surfaces of the substrate.

Abstract: Provided herein are methods of treating or preventing a T-cell mediated inflammatory disease or cancer in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antibody that specifically binds to human PSGL-1 in combination with a Janus kinase (JAK) inhibitor. In some embodiments, the T-cell mediated inflammatory disease is GVHD, e.g., acute GVHD or chronic GVHD.

Abstract: A composite optical film, comprising: a quantum-dot film and a first optical film disposed over the quantum-dot film, wherein a first plurality of multi-faceted recesses are formed on a first surface of the first optical film, wherein each multi-faceted recess comprises a shape of a reversed cone.

Abstract: The present invention discloses a quantum-dot composite film comprising: a quantum-dot prism film, comprising a quantum-dot layer and a first plurality of prisms disposed over the quantum-dot layer, wherein a first optical prism film and a second optical prism film are disposed over the quantum-dot prism film for increasing the brightness level of the quantum-dot prism film.

Abstract: A composite quantum-dot optical film comprises a quantum-dot layer and a composite structure disposed on the quantum-dot layer, wherein the composite structure comprises a first substrate, a second substrate, and a first barrier layer, wherein each of the first substrate and the second substrate comprises a polymer material, wherein the barrier layer being made of organic material and capable of being water-resistant is disposed between the first substrate and the second substrate.

Abstract: A quantum-dot optical film comprises: a binder, wherein a plurality of quantum dots, and a plurality of clay fragments are dispersed in the binder, wherein each of the clay fragments is capable of being water-resistant and oxygen-resistant.

Abstract: A quantum-dot optical film comprising a quantum-dot layer, a first base film and a first coating layer, wherein the first coating layer is coated on the base film, wherein the first coating layer is disposed on a top surface of the quantum-dot layer, the first coating layer comprising a first polymer and clay fragments dispersed in the first polymer for being water-resistant and oxygen-resistant.

Abstract: An automated optical inspection method, an automated optical inspection system, and a storage medium are provided. The method includes the following. An original image including first images of a target object is captured by an optical lens. An edge detection is performed on the original image to obtain an edge image including second images having an edge pattern. At least one of maximum, minimum, and average values of a pixel value in the second images is calculated. The edge image is divided into image blocks according to a unit area, and characteristic values are calculated according to the at least one of the maximum, minimum, and average values corresponding to the second images included in the image blocks. An optimal regression model is obtained by training a regression model corresponding to a defect of the target object according to the characteristic values and a data of the target object.