Patents by Inventor Chian-Shiu Chien

Chian-Shiu Chien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR INCREASING THE TRANSDUCTION CAPABILITY AND REPROGRAMMING EFFICIENCY IN TARGETING CELLS AND TISSUES
    Publication number: 20250230427
    Abstract: The present invention provides a system for enhancing efficiency of gene delivery and/or reprogramming of target cells or tissues, comprising a magnet field-generating device that is assembled in a 12-well culture plate and magnet components to generate a magnet field, and magnet beads, which are used to label targeting cells or tissues, or which are incorporated into agarose gel.
    Type: Application
    Filed: January 16, 2024
    Publication date: July 17, 2025
    Applicant: National Yang Ming Chiao Tung University
    Inventors: Guang-Yuh CHIOU, Chian-Shiu CHIEN
  • Medium and device for proliferation of stem cells and treatment of cancer-related stem cell with resveratrol
    Patent number: 8183297
    Abstract: The invention relates to a device for selecting stem cells with a serum free medium for amplification of stem cells. The invention also relates to a method of treating or preventing diseases caused by cancer-related stem cells. The invention further provides a method of enhancing radiosensitivity of cancer-related stem cells comprising radiotherapy with resveratrol, and the cancer-related stem cell has stronger drug resistance. The present invention further provides that resveratrol promotes differentiation and inhibits teratoma/tumor formation in induced pluripotent stem cells (iPS) and embryonic stem cells.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: May 22, 2012
    Assignee: Taipei Veterans General Hospital
    Inventors: Shih-Hwa Chiou, Tsung-Yun Liu, Tung-Hu Tsai, Jeng-Fan Lo, Yi-Ping Yang, Fu-Ting Tsai, Yu-Chih Chen, Chian-Shiu Chien
  • MEDIUM AND DEVICE FOR PROLIFERATION OF STEM CELLS AND TREATMENT OF CANCER-RELATED STEM CELL WITH RESVERATROL
    Publication number: 20100010099
    Abstract: The invention relates to a device for selecting stem cells with a serum free medium for amplification of stem cells. The invention also relates to a method of treating or preventing diseases caused by cancer-related stem cells. The invention further provides a method of enhancing radiosensitivity of cancer-related stem cells comprising radiotherapy with resveratrol, and the cancer-related stem cell has stronger drug resistance.
    Type: Application
    Filed: July 10, 2009
    Publication date: January 14, 2010
    Applicant: TAIPEI VETERANS GENERAL HOSPITAL
    Inventors: SHIH-HWA CHIOU, TSUNG-YUN LIU, TUNG-HU TSAI, JENG-FAN LO, YI-PING YANG, FU-TING TSAI, YU-CHIH CHEN, CHIAN-SHIU CHIEN