Patents by Inventor Chiao-Chain Huang

Chiao-Chain Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manipulation of nuclear architecture
    Patent number: 11293018
    Abstract: Chromatin looping is key to gene regulation, yet no broadly applicable methods to selectively modify chromatin loops have been described. Disclosed herein is an engineered method for chromatin loop reorganization using CRISPR-dCas9 (CLOuD9) to selectively and reversibly establish chromatin loops. Disclosed herein is the power of this technology to selectively modulate gene expression at targeted loci.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: April 5, 2022
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, SYSTEM BIOSCIENCES INC.
    Inventors: Kevin Chun-Kai Wang, Stefanie Morgan, Fangting Wu, Chiao-Chain Huang
  • MANIPULATION OF NUCLEAR ARCHITECTURE
    Publication number: 20180355344
    Abstract: Chromatin looping is key to gene regulation, yet no broadly applicable methods to selectively modify chromatin loops have been described. Disclosed herein is an engineered method for chromatin loop reorganization using CRISPR-dCas9 (CLOuD9) to selectively and reversibly establish chromatin loops. Disclosed herein is the power of this technology to selectively modulate gene expression at targeted loci.
    Type: Application
    Filed: June 8, 2018
    Publication date: December 13, 2018
    Inventors: Kevin Chun-Kai Wang, Stefanie Morgan, Fangting Wu, Chiao-Chain Huang
  • Neuropathic pain genes; compositions thereof; related reagents
    Publication number: 20030003538
    Abstract: The invention provides NPGs from rat and human, reagents related thereto including polynucleotides encoding NPGs, purified polypeptides, and specific antibodies. Methods of making and using these reagents, in particular, methods for screening compounds which modulate NPGs activity are provided. Also provided are methods of diagnosis, kits, and transgenic animals.
    Type: Application
    Filed: May 15, 2002
    Publication date: January 2, 2003
    Inventors: Paul Shartzer Dietrich, Chiao-Chain Huang, Carl D. Johnson, Lakshmi Sangameswaran