Patents by Inventor Chiara Ghiron

Chiara Ghiron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunomodulatory compounds
    Publication number: 20050203118
    Abstract: The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.
    Type: Application
    Filed: November 21, 2003
    Publication date: September 15, 2005
    Applicant: ACTIVE BIOTECH AB
    Inventors: Ian Matthews, Thomas Coulter, Chiara Ghiron, Chris Brennan, Muhammed Uddin, Lars Goran Pettersson, Dorthe Thrige, Philip Huxley
  • Calcium receptor modulating agents
    Publication number: 20050143426
    Abstract: The compounds of the invention are represented by the following general structure or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: February 18, 2005
    Publication date: June 30, 2005
    Inventors: Michael Kelly, Shimin Xu, Ning Xi, Philip Miller, John Kincaid, Chiara Ghiron, Thomas Coulter
  • Calcium receptor modulating agents
    Patent number: 6908935
    Abstract: The compounds of the invention are represented by the following general structure or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: June 21, 2005
    Assignee: Amgen Inc.
    Inventors: Michael G. Kelly, Shimin Xu, Ning Xi, Philip Miller, John F. Kincaid, Chiara Ghiron, Thomas Coulter
  • Substituted heterocyclic compounds and methods of use
    Publication number: 20050070554
    Abstract: The present invention relates to tetracyclic pyrimidines or pyridines or pharmaceutically-acceptable salts or derivatives thereof. Also included are methods of use of the tetracyclic pyrimidines or pyridines including use related to treating inflammation, inhibiting T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease and many other related disorders in a subject, the methods comprising administering a therapeutically-effective amount a compound as described above to the subject.
    Type: Application
    Filed: August 20, 2004
    Publication date: March 31, 2005
    Inventors: Joseph Nunes, Xiaotian Zhu, Monika Ermann, Chiara Ghiron, David Johnston, Carl-Gustaf Saluste
  • Immunomodulatory compounds
    Publication number: 20040116461
    Abstract: The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.
    Type: Application
    Filed: November 21, 2003
    Publication date: June 17, 2004
    Applicant: ACTIVE BIOTECH AB
    Inventors: Ian Richard Matthews, Thomas Stephen Coulter, Chiara Ghiron, Chris James Brennan, Muhammed Kamal Uddin, Lars Olof Goran Pettersson, Dorthe da Graca Thrige, Philip Huxley
  • Calcium receptor modulating agents
    Publication number: 20040082625
    Abstract: The compounds of the invention are represented by the following general structure 1
    Type: Application
    Filed: May 22, 2003
    Publication date: April 29, 2004
    Inventors: Michael G. Kelly, Shimin Xu, Ning Xi, Philip Miller, John F. Kincaid, Chiara Ghiron, Thomas Coulter
  • Calcium receptor modulating agents
    Publication number: 20040077619
    Abstract: The compounds of the invention are represented by the following general structure 1
    Type: Application
    Filed: May 22, 2003
    Publication date: April 22, 2004
    Inventors: Michael G. Kelly, Shimin Xu, Ning Xi, Robert Townsend, David Semin, Chiara Ghiron, Thomas Coulter