Patents by Inventor Chiara Malvolti

Chiara Malvolti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120184502
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Application
    Filed: March 26, 2012
    Publication date: July 19, 2012
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara MALVOLTI, Raffaella Garzia
  • Patent number: 8168598
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: May 1, 2012
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Publication number: 20110212912
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Patent number: 7939502
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: May 10, 2011
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Publication number: 20100098642
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Application
    Filed: December 18, 2009
    Publication date: April 22, 2010
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Patent number: 7696178
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: April 13, 2010
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Patent number: 6987094
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: January 17, 2006
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Patent number: 6967017
    Abstract: The present invention relates to optimized formulations of antiinflammatory steroids for nebulisation and a process for the preparation thereof. More particularly, the invention relates to formulations for monodose or multidose vials in the form of preservative-free stable solutions of a more acceptable osmolarity, which can effectively be nebulised with the nebulisers currently available on the market and are well-tolerated by patients.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: November 22, 2005
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia, Gaetano Brambilla, Paolo Chiesi
  • Publication number: 20050163722
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Application
    Filed: March 18, 2005
    Publication date: July 28, 2005
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Publication number: 20040186064
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Application
    Filed: April 28, 2004
    Publication date: September 23, 2004
    Inventors: Chiara Malvolti, Raffaella Garzia
  • Patent number: 6464958
    Abstract: The invention is directed to a process for the preparation of suspensions of drug particles for inhalation delivery, said process providing particles of optimized particle size and distribution homogeneously dispersed in the carrier. The process, which is also suitable for the preparation of sterile suspensions, includes the step of homogenizing and micronizing the formulation in a turboemulsifier provided with a high-potency turbine, optionally followed by a treatment in a high-pressure homogenizer. A further aspect of the invention is directed to a process for preparing micronized sterile beclomethasone dipropionate by gamma-irradiation.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: October 15, 2002
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Eva Bernini, Chiara Malvolti, Raffaella Garzia, Gaetano Brambilla, Paolo Chiesi