Patents by Inventor Chiara Zavattaro

Chiara Zavattaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
    Patent number: 10562897
    Abstract: The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: February 18, 2020
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: François Paul Bischoff, Adriana Ingrid Velter, Frederik Jan Rita Rombouts, Michel Anna Jozef De Cleyn, Sven Franciscus Anna Van Brandt, Henricus Jacobus Maria Gijsen, Chiara Zavattaro, Frans Alfons Maria Van den Keybus
  • Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
    Patent number: 10246454
    Abstract: The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: April 2, 2019
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: François Paul Bischoff, Adriana Ingrid Velter, Frederik Jan Rita Rombouts, Michel Anna Jozef De Cleyn, Sven Franciscus Anna Van Brandt, Henricus Jacobus Maria Gijsen, Chiara Zavattaro, Frans Alfons Maria Van den Keybus
  • NOVEL SUBSTITUTED PYRIDO-PIPERAZINONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
    Publication number: 20180319797
    Abstract: The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 8, 2018
    Inventors: François Paul Bischoff, Adriana Ingrid Velter, Frederik Jan, Rita Rombouts, Michel Anna, Jozef De Cleyn, Sven Franciscus, Anna Van Brandt, Henricus Jacobus, Maria Gijsen, Chiara Zavattaro, Frans Alfons, Maria Van den Keybus
  • NOVEL SUBSTITUTED PYRIDO-PIPERAZINONE DERIVATIVES AS GAMMA SECRETASE MODULATORS
    Publication number: 20150353544
    Abstract: The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 10, 2015
    Applicant: Janssen Pharmaceutica NV
    Inventors: François Paul Bischoff, Adriana Ingrid Velter, Frederik Jan, Rita Rombouts, Michel Anna, Jozef De Cleyn, Sven Franciscus, Anna Van Brandt, Henricus Jacobus, Maria Gijsen, Chiara Zavattaro, Frans Alfons, Maria Van den Keybus