Patents by Inventor ChiChang Lee

ChiChang Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid way to obtain high expression clones of mammalian cells using a methylcellulose and immunoprecipitation screening method
    Patent number: 9128090
    Abstract: The invention provides a genetic screening method for identifying a transfected cell expressing the polypeptide of interest. The methods allows for high throughput screening of recombinant cells for elevated levels of expression of the polypeptide of interest. The invention also provides capture media, formulations and methods of making and using thereof.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: September 8, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Chichang Lee, Celia Ly, Gordon Moore
  • Methods and compositions for enhanced protein expression and/or growth of cultured cells using co-transcription of a Bcl2 encoding nucleic acid
    Patent number: 6964199
    Abstract: The present invention in the field of biotechnology, provides methods and compositions for providing enhanced growth of, and/or protein production from, cultured mammalian host cells used for the production of commercially useful amounts of expressed proteins, by the use of at least one Bcl2 encoding nucleic acid provided or transcribed in the host cell.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: November 15, 2005
    Assignee: Cantocor, Inc.
    Inventors: ChiChang Lee, Xiaomei Shi, Celia Ly, Gordon Moore
  • Rapid way to obtain high expression clones of mammalian cells using a methylcellulose and immunoprecipitation screening method
    Publication number: 20050118652
    Abstract: The invention provides a genetic screening method for identifying a transfected cell expressing the polypeptide of interest. The methods allows for high throughput screening of recombinant cells for elevated levels of expression of the polypeptide of interest. The invention also provides capture media, formulations and methods of making and using thereof.
    Type: Application
    Filed: August 27, 2004
    Publication date: June 2, 2005
    Inventors: Chichang Lee, Celia Ly, Gordon Moore
  • Chemically defined medium for cultured mammalian cells
    Patent number: 6900056
    Abstract: The present invention relates to methods and compositions for chemically defined media for growth of mammalian cells for production of commercially useful amounts of expressed proteins.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: May 31, 2005
    Assignee: Centocor, Inc.
    Inventors: ChiChang Lee, Celia Ly, Gordon Moore, Robert Perkinson
  • Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
    Publication number: 20040152170
    Abstract: The present invention relates to clonal myeloma cell lines that have the ability to grow continuously in chemically defined media. The present invention also relates to the production of proteins in clonal myeloma cell lines and any cell lines derived therefrom. The present invention further relates to methods for identifying cell lines capable of growing in chemically defined media.
    Type: Application
    Filed: December 4, 2003
    Publication date: August 5, 2004
    Inventors: Chichang Lee, Gordon Moore, Edward Savino, Xiaomei Shi
  • Methods and compositions for enhanced protein expression and/or growth of cultured cells using co-transcription of a Bcl2 encoding nucleic acid
    Publication number: 20040043028
    Abstract: The present invention in the field of biotechnology, provides methods and compositions for providing enhanced growth of, and/or protein production from, cultured mammalian host cells used for the production of commercially useful amounts of expressed proteins, by the use of at least one Bcl2 encoding nucleic acid provided or transcribed in the host cell.
    Type: Application
    Filed: November 2, 2001
    Publication date: March 4, 2004
    Inventors: ChiChang Lee, Xiaomei Shi, Celia Ly, Gordon Moore
  • Myeloma cell line useful for manufacturing recombinant proteins in chemically defined media
    Publication number: 20030166146
    Abstract: The present invention provides a novel myeloma cell line, designated C463A, and derivatives of C463A, which have the ability to grow continuously in chemically defined media. The present invention also relates to the production of proteins in cell line C463A and any cell line derived therefrom. The present invention further relates to methods for identifying cell lines capable of growing in chemically defined media. The present invention also relates to business methods where customers are provided with the cells, cell lines, and cell cultures of the present invention.
    Type: Application
    Filed: December 11, 2002
    Publication date: September 4, 2003
    Inventors: ChiChang Lee, Edward Savino, Gordon Moore, Celia Ly
  • Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
    Publication number: 20030166147
    Abstract: The present invention relates to clonal myeloma cell lines that have the ability to grow continuously in chemically defined media. The present invention also relates to the production of proteins in clonal myeloma cell lines and any cell lines derived therefrom. The present invention further relates to methods for identifying cell lines capable of growing in chemically defined media. The present invention also relates to business methods where customers are provided with the cells, cell lines, and cell cultures of the present invention.
    Type: Application
    Filed: December 11, 2002
    Publication date: September 4, 2003
    Inventors: ChiChang Lee, Edward Savino, Gordon Moore, Celia Ly
  • Chemically defined medium for cultured mammalian cells
    Publication number: 20030096402
    Abstract: The present invention relates to methods and compositions for chemically defined media for growth of mammalian cells for production of commercially useful amounts of expressed proteins.
    Type: Application
    Filed: February 5, 2002
    Publication date: May 22, 2003
    Inventors: ChiChang Lee, Celia Ly, Gordon Moore, Robert Perkinson