Patents by Inventor Chieko Itoh

Chieko Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing oxazopyrroloquinolines, novel oxazopyrroloquinolines, and use of oxazopyrroloquinolines
    Patent number: 5429940
    Abstract: The present invention provides a process for producing oxazopyrroloquinolines which comprises culturing microorganisms to produce pyrroloquinolinequinone and adding .alpha.-amino acids or monomethylamine to the resulting culture broth which contains the pyrroloquinolinequinone and from which cells of microorganisms are not separated, thereby to convert the pyrroloquinolinequinone to the corresponding oxazopyrroloquinolines. The thus obtained oxazopyrroloquinolines include novel compounds. The present invention further provides aldose reductase inhibitors, diabetic combined disease curing agents, immunopotentiating agents and liver disease inhibiting agents which contain as active ingredient these oxazopyrroloquinolines having excellent physiological activity.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: July 4, 1995
    Assignee: Mitsubishi Gas Chemical Company
    Inventors: Teizi Urakami, Mitsunori Oda, Chieko Itoh, Hisao Kobayashi, Toshio Nagai, Kazuhiro Sugamura
  • Oxazopyrroloquinolines and use of oxazopyrroloquinolines
    Patent number: 5236930
    Abstract: The present invention provides a process for producing oxazopyrroloquinolines which comprises culturing microorganisms to produce pyrroloquinolinequinone and adding .alpha.-amino acids or monomethylamine to the resulting culture broth which contains the pyrroloquinolinequinone and from which cells of microorganisms are not separated, thereby to convert the pyrroloquinolinequinone to the corresponding oxazopyrroloquinolines.The thus obtained oxazopyrroloquinolines include novel compounds.The present invention further provides aldose reductase inhibitors, diabetic combined disease curing agents, immunopotentiating agents and liver disease inhibiting agents which contain as active ingredient these oxazopyrroloquinolines having excellent physiological activity.
    Type: Grant
    Filed: January 23, 1992
    Date of Patent: August 17, 1993
    Assignee: Mitbushi Gas Chemical Company, Inc.
    Inventors: Teizi Urakami, Mitsunori Oda, Chieko Itoh, Hisao Kobayashi, Toshio Nagai, Kazuhiro Sugamura
  • Method of curing liver diseases by using pyrrolo quinoline quinone triesters and novel pyrrolo quinoline quinone triesters
    Patent number: 5061711
    Abstract: Disclosed is a method of curing liver diseases by administration of pyrrolo quinoline quinon triesters (PQQ triesters). The PQQ triesters include PQQ triallyl ester and PQQ tribenzyl ester which are novel. The PQQ triesters being ester form, they have no toxicity and can be orally adminstered.
    Type: Grant
    Filed: October 3, 1990
    Date of Patent: October 29, 1991
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Teizi Urakami, Mitsunori Oda, Chieko Itoh