Abstract: It is an object of the present invention to provide a medicament or a pharmaceutical composition, which is effective for the treatment of various cancers. More specifically, the present invention relates to a pharmaceutical composition for use in the treatment of cancers, which comprises rMV-SLAM-blind or rMV-V(?)-SLAM-blind. The pharmaceutical composition has the effect of causing the regression of tumor, even if it is intravenously administered, and it also exhibits effects on cancer metastasized from a primary lesion.

Abstract: It is an object of the present invention to provide a medicament or a pharmaceutical composition, which is effective for the treatment of various cancers. More specifically, the present invention relates to a pharmaceutical composition for use in the treatment of cancers, which comprises rMV-SLAM-blind or rMV-V(?)-SLAM-blind. The pharmaceutical composition has the effect of causing the regression of tumor, even if it is intravenously administered, and it also exhibits effects on cancer metastasized from a primary lesion.

Abstract: Provided herein is a vaccine which is safe and effective against malarial infection and a vector which is used in the manufacture of this vaccine and to provide a bivalent vaccine which exhibits an excellent preventive effect against measles virus and malarial infection and which eliminates complexity at the time of inoculation. Also provided is a recombinant measles virus in which is inserted a gene which encodes a protein involved in preventing malarial infection in the measles virus genome. The present invention also provides a bivalent vaccine against measles and malarial infection which contains the recombinant measles virus.

Abstract: Provided herein is a vaccine which is safe and effective against Nipah virus infection and a vector which is used in the manufacture of this vaccine and to provide a bivalent vaccine which exhibits an excellent preventive effect against measles virus and Nipah virus infection and which eliminates complexity at the time of inoculation. Also provided is a recombinant measles virus in which is inserted a gene which encodes a protein involved in preventing Nipah infection into the measles virus genome. The protein involved in preventing Nipah virus infection is preferably G protein or F protein which is a membrane protein. Also provided is a bivalent vaccine against measles and Nipah virus infection which contains the recombinant measles virus.

Abstract: The present invention provides a vaccine against canine distemper and leishmaniasis by constructing a recombinant canine distemper virus containing a gene encoding a protein associated with protection against Leishmania protozoa infection inserted into the canine distemper virus vector.

Abstract: The present invention provides a vaccine against canine distemper and leishmaniasis by constructing a recombinant canine distemper virus containing a gene encoding a protein associated with protection against Leishmania protozoa infection inserted into the canine distemper virus vector.

Abstract: The present invention provides a process for preparing a cytokine inexpensively in large amounts by expressing the cytokine in a hen's egg using Sendai virus vector. The cytokine obtained by the present process is expected to be useful as medication because it has sugar chains very similar to those of mammals.