Patents by Inventor Chieko Kunugita

Chieko Kunugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azetidinone derivatives as .beta.-lactamase inhibitors
    Patent number: 5994340
    Abstract: New 2-oxo-1-azetidine sulfonic acid derivatives with an aminoalkyl substituted "anti" (E-isomer) oxyimino group in the acylamino substituent at the 3 position of the monobactam ring. These compounds are potent inhibitors of bacterial .beta.-lactamases. These compounds can be used in combination with .beta.-lactam antibiotics to increase the effectiveness of the .beta.-lactam antibiotics in fighting infection caused by .beta.-lactamase producing bacteria.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: November 30, 1999
    Assignee: SynPhar Laboratories, Inc.
    Inventors: Samarendra N. Maiti, Oludotun A. Phillips, Eduardo L. Setti, Andhe V. Narender Reddy, Ronald G. Micetich, Fusahiro Higashitani, Chieko Kunugita, Koichi Nishida, Tatsuya Uji
  • 2-oxo-1-azetidine sulfonic acid derivatives as potent .beta.-lactamase inhibitors
    Patent number: 5888998
    Abstract: A compound of formula (I) ##STR1## wherein R.sub.1 is selected from the group consisting of 2-thienyl, 2-furyl, 2-pyrrolyl, 1-methyl-2-pyrrolyl, 2-amino-1-thiazolyl and 5-isothiazolyl;R.sub.2 is selected from the group consisting of: ##STR2## and M is hydrogen or a pharmaceutically acceptable cation; wherein the oxyimino fragment (.dbd.N--OR.sub.2) in formula (I) is in the `anti` orientation.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: March 30, 1999
    Assignees: Synphar Laboratories, Inc., Taiho Pharmaceutical Co., Ltd.
    Inventors: Samarendra N. Maiti, Eduardo L. Setti, Oludotun A. Phillips, Andhe V. Narender Reddy, Ronald G. Micetich, Rajeshwar Singh, Fusahiro Higashitani, Chieko Kunugita, Koichi Nishida, Tatsuya Uji
  • Penam sulfones as .beta.-lactamase inhibitors
    Patent number: 5686441
    Abstract: Novel 3-(substituted)-3-methyl-4-thia-1-azabicyclo?3.2.0!heptane-2-carboxylate, 4,4-dioxides which are of value for use in combination with .beta.-lactam antibiotics to increase the effectiveness of the antibiotics.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: November 11, 1997
    Assignees: Syphar Laboratories, Inc., Taiho Pharmaceutical Co., Ltd.
    Inventors: Samarendra Nath Maiti, Oludotun Adebayo Phillips, Andhe Venkat Narender Reddy, Eduardo Luis Setti, Ronald George Micetich, Chieko Kunugita, Fusahiro Higashitani, Akio Hyodo