Patents by Inventor Chieko Tsuchiya

Chieko Tsuchiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8895076
    Abstract: A liquid composition containing a polymer micelle and having a pH values of 3.0 to 7.0 is provided. The micelle is constituted of a coordination compound having a block copolymer of polyethylene glycol and polyglutamic acid and cisplatin that is coordinate-bonded to the block copolymer.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: November 25, 2014
    Assignees: Nanocarrier Co., Ltd., The University of Tokyo
    Inventors: Kazunori Kataoka, Nobuhiro Nishiyama, Chieko Tsuchiya, Tatsuyuki Hayashi
  • Publication number: 20140141072
    Abstract: Provided are a composition for preparing a lyophilized preparation, comprising a drug-encapsulating polymer micelle and saccharides and/or polyethylene glycol as a stabilizing agent, a lyophilized preparation and a process for producing them. The lyophilized preparation thus provided is easily restructured to an aqueous preparation using an aqueous medium.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: NANOCARRIER CO., LTD.
    Inventors: Yasuaki OGAWA, Shoko NAGASAKI, Yoshihiko NOGATA, Katsuhiko SAGAWA, Chieko TSUCHIYA
  • Publication number: 20120141556
    Abstract: Provided are a composition for preparing a lyophilized preparation, comprising a drug-encapsulating polymer micelle and saccharides and/or polyethylene glycol as a stabilizing agent, a lyophilized preparation and a process for producing them. The lyophilized preparation thus provided is easily restructured to an aqueous preparation using an aqueous medium.
    Type: Application
    Filed: January 25, 2012
    Publication date: June 7, 2012
    Inventors: Yasuaki OGAWA, Shoko Nagasaki, Yoshihiko Nogata, Katsuhiko Sagawa, Chieko Tsuchiya
  • Publication number: 20110110881
    Abstract: A liquid composition containing a polymer micelle and having a pH values of 3.0 to 7.0 is provided. The micelle is constituted of a coordination compound having a block copolymer of polyethylene glycol and polyglutamic acid and cisplatin that is coordinate-bonded to the block copolymer.
    Type: Application
    Filed: May 27, 2009
    Publication date: May 12, 2011
    Inventors: Kazunori Kataoka, Nobuhiro Nishiyama, Chieko Tsuchiya, Tatsuyuki Hayashi
  • Patent number: 7781607
    Abstract: There is provided a production method in which bis(nitrato)platinum complex, optionally in the concurrent presence of dihalo-platinum complex, and poly(ethylene glycol)-block-poly(glutamic acid) are used at specific ratios and reacted. Coordination compound of an anti-tumor platinum complex with a block copolymer having carboxyl groups on its side chains is efficiently produced.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: August 24, 2010
    Assignees: Nanocarrier Co., Ltd., The University of Tokyo
    Inventors: Katsutoshi Kobayashi, Shoko Nagasaki, Kazunori Kataoka, Chieko Tsuchiya
  • Publication number: 20080249256
    Abstract: There is provided a production method in which bis(nitrato)platinum complex, optionally in the concurrent presence of dihalo-platinum complex, and poly(ethylene glycol)-block-poly(glutamic acid) are used at specific ratios and reacted. Coordination compound of an anti-tumor platinum complex with a block copolymer having carboxyl groups on its side chains is efficiently produced.
    Type: Application
    Filed: June 8, 2006
    Publication date: October 9, 2008
    Inventors: Katsutoshi Kobayashi, Shoko Nagasaki, Kazunori Kataoka, Chieko Tsuchiya
  • Publication number: 20060269613
    Abstract: A drug and a biodegradable polymer having at least one carboxyl group are encapsulated into nanoparticle which is formed by a block copolymer having a hydrophilic segment and a hydrophobic segment. This invention thus provides a drug-encapsulated nanoparticle which shows an increased in vivo drug-stability.
    Type: Application
    Filed: September 6, 2004
    Publication date: November 30, 2006
    Inventors: Yasuaki Ogawa, Shoko Nagasaki, Chieko Tsuchiya, Sohei Higashi, Hiroyuki Saito
  • Publication number: 20060057219
    Abstract: A production method of a preparation containing drug-encapsulating polymer micelles is provided, which comprises dissolving a hydrophilic-hydrophobic block copolymer and a sparingly water-soluble drug in a volatile organic solvent, then removing the solvent, and stirring the residue with water at a temperature not higher than 30° C. to dissolve the drug-encapsulating polymer micelles into the water.
    Type: Application
    Filed: May 21, 2003
    Publication date: March 16, 2006
    Applicant: NanoCarrier Co., Ltd.
    Inventors: Shoko Nagasaki, Chieko Tsuchiya, Katsuhiko Sagawa
  • Publication number: 20040253315
    Abstract: Provided are a composition for preparing a lyophilized preparation, comprising a drug-encapsulating polymer micelle and saccharides and/or polyethylene glycol as a stabilizing agent, a lyophilized preparation and a process for producing them. The lyophilized preparation thus provided is easily restructured to an aqueous preparation using an aqueous medium.
    Type: Application
    Filed: January 13, 2004
    Publication date: December 16, 2004
    Inventors: Yasuaki Ogawa, Shoko Nagasaki, Yoshihiko Nogata, Katsuhiko Sagawa, Chieko Tsuchiya