Patents by Inventor Chien-Fen Chen

Chien-Fen Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oral dosage formulation containing both immediate-release and sustained-release drugs for treating neurodegenerative disorders
    Patent number: 8815288
    Abstract: Disclosed herein is an oral dosage formulation that contains both immediate-release and sustained release drugs for treating neurodegenerative disorders. The immediate-release drug in the oral dosage formulation is an acetylcholinesterase inhibitor (AChEI) with a dissolution rate of releasing more than 80% of the AChEI within 60 min; and the sustained-release drug is memantine with a dissolution rate of releasing more than 80% of memantine within 12 hours.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: August 26, 2014
    Assignee: Center Laboratories, Inc.
    Inventors: Huai-Cheng Lee, Chien-Fen Chen, Chuen-Lin Din, Rong Jin Lin
  • Method for treating neurodegenerative disorders with oral dosage formulation containing both immediate-release and sustained-release drugs
    Patent number: 8802143
    Abstract: Disclosed herein is a method for treating patient suffering from a disorder related to central nervous system with an oral dosage formulation that contains both sustained-release and immediate-release drugs. The sustained-release drug in the oral dosage formulation is memantine, and the formulation provides an average blood level Cmax of the memantine in a range of about 10-24 ng/mL during an average Tmax of about 10-45 hours. The immediate-release drug in the oral dosage formulation is an acetylcholinesterase inhibitor (AChEI), and the formulation provides an average blood level Cmax of the AChEI in a range of about 12-38 ng/mL during an average Tmax of less than about 4 hours.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: August 12, 2014
    Assignee: Center Laboratories, Inc.
    Inventors: Guang-Tzuu Shane, Chien-Fen Chen, Chuen-Lin Din, Hui-Ling Tsai, Pei-Chen Tsai
  • ORAL DOSAGE FORMULATION CONTAINING BOTH IMMEDIATE-RELEASE AND SUSTAINED-RELEASE DRUGS FOR TREATING NEURODEGENERATIVE DISORDERS
    Publication number: 20120177735
    Abstract: Disclosed herein is an oral dosage formulation that contains both immediate-release and sustained release drugs for treating neurodegenerative disorders. The immediate-release drug in the oral dosage formulation is an acetylcholinesterase inhibitor (AChEI) with a dissolution rate of releasing more than 80% of the AChEI within 60 min; and the sustained-release drug is memantine with a dissolution rate of releasing more than 80% of memantine within 12 hours.
    Type: Application
    Filed: September 29, 2010
    Publication date: July 12, 2012
    Applicant: Center Laboratories, Inc.
    Inventors: Huai-Cheng Lee, Chien-Fen Chen, Chuen-Lin Din, Rong Jin Lin
  • METHOD FOR TREATING NEURODEGENERATIVE DISORDERS WITH ORAL DOSAGE FORMULATION CONTAINING BOTH IMMEDIATE-RELEASE AND SUSTAINED-RELEASE DRUGS
    Publication number: 20110171302
    Abstract: Disclosed herein is a method for treating patient suffering from a disorder related to central nervous system with an oral dosage formulation that contains both sustained-release and immediate-release drugs. The sustained-release drug in the oral dosage formulation is memantine, and the formulation provides an average blood level Cmax of the memantine in a range of about 10-24 ng/mL during an average Tmax of about 10-45 hours. The immediate-release drug in the oral dosage formulation is an acetylcholinesterase inhibitor (AChEI), and the formulation provides an average blood level Cmax of the AChEI in a range of about 12-38 ng/mL during an average Tmax of less than about 4 hours.
    Type: Application
    Filed: March 25, 2011
    Publication date: July 14, 2011
    Applicant: Center Laboratories, Inc.
    Inventors: Guang-Tzuu SHANE, Chien-Fen Chen, Chuen-Lin Din, Hui-Ling Tsai, Pei-Chen Tsai