Patents by Inventor Chien-Han Kao

Chien-Han Kao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11369690
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: June 28, 2022
    Assignee: ACADEMIA SINICA & KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Steven R Roffler, Tian-Lu Cheng, Chien-Han Kao, Bing-Mae Chen, Yu-Cheng Su, Hsin-Yi Tung, Kuo-Hsiang Chuang
  • Patent number: 11040111
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: June 22, 2021
    Assignees: ACADEMIA SINICA, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Steven R Roffler, Tian-Lu Cheng, Chien-Han Kao, Bing-Mae Chen, Yu-Cheng Su, Hsin-Yi Tung, Kuo-Hsiang Chuang
  • Publication number: 20210154319
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Application
    Filed: August 24, 2018
    Publication date: May 27, 2021
    Applicants: ACADEMIA SINICA, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: STEVEN R ROFFLER, TIAN-LU CHENG, CHIEN-HAN KAO, BING-MAE CHEN, YU-CHENG SU, HSIN-YI TUNG, Kuo-Hsiang Chuang
  • Publication number: 20200061205
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Application
    Filed: August 24, 2018
    Publication date: February 27, 2020
    Applicants: ACADEMIA SINICA, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: STEVEN R. ROFFLER, TIAN-LU CHENG, CHIEN-HAN KAO, BING-MAE CHEN, YU-CHENG SU, HSIN-YI TUNG, KUO-HSIANG CHUANG
  • Patent number: 10188742
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: January 29, 2019
    Assignee: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Steven R Roffler, Tian-Lu Cheng, Chien-Han Kao, Bing-Mae Chen, Yu-Cheng Su, Hsin-Yi Tung, Kuo-Hsiang Chuang
  • Publication number: 20190022245
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppressing the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Application
    Filed: August 24, 2018
    Publication date: January 24, 2019
    Applicants: ACADEMIA SINICA, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: STEVEN R ROFFLER, TIAN-LU CHENG, CHIEN-HAN KAO, BING-MAE CHEN, YU-CHENG SU, HSIN-YI TUNG, Kuo-Hsiang Chuang
  • Publication number: 20170056523
    Abstract: Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
    Type: Application
    Filed: March 2, 2015
    Publication date: March 2, 2017
    Applicants: ACADEMIA SINICA, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: STEVEN R ROFFLER, TIAN-LU CHENG, CHIEN-HAN KAO, BING-MAE CHEN, YU-CHENG SU, HSIN-YI TUNG, Kuo-Hsiang Chuang
  • Publication number: 20090190303
    Abstract: A gap adjusting jig for heat dissipation is suitable to hold at least a heat source of a plate-shaped module. The gap adjusting jig for heat dissipation includes a first heat dissipation plate and a second heat dissipation plate and at least a gap adjusting element. A gap is formed between the first and second heat dissipation plates. The heat source is suitable to be provided in the gap and lean against the first and second heat dissipation plates. The gap adjusting element is connected between the first and second heat dissipation plates. The gap adjusting element is suitable to adjust the gap between the first and second heat dissipation plates to enable the first and second heat dissipation plates to hold the heat source.
    Type: Application
    Filed: June 3, 2008
    Publication date: July 30, 2009
    Applicant: ASUSTeK COMPUTER INC.
    Inventors: Hung-Chun Chu, Chun-Teng Chiu, Zhi-Kai Chen, Chien-Han Kao