Abstract: A method for manufacturing a synthetic leatherette that possesses properties of high elasticity, abrasion resistance and environmental friendliness, comprises following steps: melting grains of Thermoplastic Elastomer (TPE) in a melting pot into a TPE melt with heat; mixing the TPE melt into an even TPE liquid; sheeting the TPE liquid into a TPE layer with a heat pressing roller; laminating the TPE layer with a reinforcement material layer with heat; cooling the TPE layer laminated with the reinforcement material layer with a cooling rooler; and reheating the cooled TPE layer laminated with the reinforcement material layer in a oven for finalize the synthetic leatherette. In industrial applications, the disclosed synthetic leatherette made of TPE is advantaged by being innocuous, without uncomfortable odor, decomposable, completely recyclable, highly elastic, highly wear-resistant, and light.