Patents by Inventor Chien-Liang Glenn Lin

Chien-Liang Glenn Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EAAT2 activators and methods of using thereof
    Patent number: 11702403
    Abstract: Disclosed are compounds that activate excitatory amino acid transporter 2 (EAAT2), as well as methods of using these compounds to treat or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: July 18, 2023
    Assignees: OHIO STATE INNOVATION FOUNDATION, THE BRIGHAM AND WOMAN'S HOSPITAL, INC.
    Inventors: Kevin Hodgetts, Chien-Liang Glenn Lin
  • EAAT2 ACTIVATORS AND METHODS OF USING THEREOF
    Publication number: 20230138663
    Abstract: Disclosed are compounds that activate excitatory amino acid transporter 2 (EAAT2), as well as methods of using these compounds to treat or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Application
    Filed: October 4, 2022
    Publication date: May 4, 2023
    Inventors: Kevin HODGETTS, Chien-Liang Glenn LIN
  • EAAT2 enhancing molecules
    Patent number: 11377436
    Abstract: The present application provides pyridine, pyrimidine, and pyrazine derivatives that activate excitatory amino acid transporter 2 (EAAT2), and methods of using the derivatives for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: July 5, 2022
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., OHIO STATE UNIVERSITY
    Inventors: Kevin Hodgetts, Chien-Liang Glenn Lin
  • EAAT2 ACTIVATORS AND METHODS OF USING THEREOF
    Publication number: 20210171497
    Abstract: Disclosed are compounds that activate excitatory amino acid transporter 2 (EAAT2), as well as methods of using these compounds to treat or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Application
    Filed: June 4, 2019
    Publication date: June 10, 2021
    Inventors: Kevin HODGETTS, Chien-Liang Glenn LIN
  • EAAT2 ENHANCING MOLECULES
    Publication number: 20210163440
    Abstract: The present application provides pyridine, pyrimidine, and pyrazine derivatives that activate excitatory amino acid transporter 2 (EAAT2), and methods of using the derivatives for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Application
    Filed: July 12, 2018
    Publication date: June 3, 2021
    Inventors: Kevin HODGETTS, Chien-Liang Glenn LIN
  • Pyridazine derivatives as EAAT2 activators
    Patent number: 10787433
    Abstract: Pyradizine derivatives that activity the excitatory amino acid transporter 2 (EAAT2) of the formula: and methods of use thereof for treating or preventing diseases, disorders, and conditions with glutamate toxicity.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 29, 2020
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., OHIO STATE UNIVERSITY
    Inventors: Kevin Hodgetts, Chien-Liang Glenn Lin
  • PYRIDAZINE DERIVATIVES AS EAAT2 ACTIVATORS
    Publication number: 20190040040
    Abstract: Pyridazine derivatives that activate the excitatory amino acid transporter 2 (EAAT2), and methods of use thereof for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Application
    Filed: January 13, 2017
    Publication date: February 7, 2019
    Inventors: Kevin HODGETTS, Chien-Liang Glenn LIN
  • Pyridazine derivatives as EAAT2 activators
    Patent number: 9447075
    Abstract: Pyridazine derivatives that activate the excitatory amino acid transporter 2 (EAAT2), and methods use thereof for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: September 20, 2016
    Assignees: The Brigham and Women's Hospital, Inc., The Ohio State University
    Inventors: Gregory D. Cuny, Marcie Glicksman, Xeuchao Xing, Chien-Liang Glenn Lin
  • Pyridazine derivatives as EAAT2 Activators
    Publication number: 20140303174
    Abstract: Pyridazine derivatives that activate the excitatory amino acid transporter 2 (EAAT2), and methods of use thereof for treating or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity.
    Type: Application
    Filed: August 2, 2012
    Publication date: October 9, 2014
    Applicant: THE BRIGHAM AND WOMEN S HOSPITAL, INC.
    Inventors: Gregory D. Cuny, Marcie Glicksman, Xeuchao Xing, Chien-Liang Glenn Lin