Patents by Inventor Chien Ting Chin
Chien Ting Chin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9022939Abstract: Method and system for ultrasound imaging of body tissue in which a focused ultrasound (FUS) transducer (20) is oriented relative to the body such that ultrasonic waves generated by the FUS transducer (20) are directed toward the tissue being imaged. The FUS transducer (20) is operated to cause the formation of microbubbles (28) in the tissue and an ultrasound image of the tissue with the microbubbles (28) is acquired. Phase aberration in the acquired ultrasound image may be corrected, if necessary, using each microbubble (28) as a point source or point-like scatterer. Microbubble (28) formation can therefore be obtained in a non-invasive manner since FUS-induced microbubble (28) formation does not require the insertion of interventional tools into the body.Type: GrantFiled: March 2, 2006Date of Patent: May 5, 2015Assignee: Koninklijke Philips N.V.Inventors: Christopher Hall, Shunmugavelu Sokka, David Louis Marie Savery, Chien-Ting Chin
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Patent number: 8764665Abstract: An acoustic probe (100, 300) includes an acoustic transducer (15, 444), and a plurality of variably-refracting acoustic lens elements (10, 210a, 210b, 442) coupled to the acoustic transducer. Each variably-refracting acoustic lens element has at least a pair of electrodes (150, 160) adapted to adjust at least one characteristic of the variably-refracting acoustic lens element in response to a selected voltage applied across the electrodes. In one embodiment, each variably-refracting acoustic lens element includes a cavity, first and second fluid media (141, 142) disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.Type: GrantFiled: April 30, 2008Date of Patent: July 1, 2014Assignee: Koninklijke Philips N.V.Inventors: Christopher Stephen Hall, Chien Ting Chin, Jan Frederik Suijver, Bernardus Hendrikus Wilhelmus Hendriks, Stein Kuiper
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Patent number: 8500641Abstract: An apparatus for application of three-dimensional ultrasound imaging and therapy comprising a two-dimensional ultrasound imaging array of transducer elements having an image signal transmitter and receiver that forms, steers and selectively focuses ultrasound beams to a three-dimensional moving or stationary spatial volume; one or more two-dimensional ultrasound therapy arrays of transducer elements, each array having a therapy signal transmitter that forms, steers and selectively focuses and delivers ultrasound therapy to the volume; wherein the location of the array of imaging and therapy transducer elements are known relative to one another; and a controller that controls the image transmitter and receiver to provide three-dimensional images of the volume and simultaneously independently controls each of the one or more therapy transmitters to deliver therapy to the volume.Type: GrantFiled: November 6, 2007Date of Patent: August 6, 2013Assignee: Koninklijke Philips N.V.Inventors: Balasundara Raju, Christopher Hall, Chien Ting Chin, William T. Shi
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Publication number: 20120029397Abstract: Growth in body tissue is slowed, arrested or reversed. In one aspect, this is accomplished by providing bubbles (S315), and delivering, to cause temporary change in physiology that at least one of retards, arrests and reverses said growth, a series of one or more pulses (206) of energy to respective focal points (213) at the site of the growth. In another aspect, temporary change in physiology, such as transient vasospasm (216) in vasculature of a neoplasm, is induced via the mechanical, non-thermal effects of fluid cavitation caused by the pulses. The bubbles, for facilitating the cavitation, in some embodiments, are afforded by administration of a microbubble agent to the host.Type: ApplicationFiled: April 2, 2010Publication date: February 2, 2012Applicants: THE UNIVERSITY OF VIRGINIA, KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Chien Ting Chin, Christopher Stephen Hall, Alexander L. Klibanov
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Patent number: 7957219Abstract: An acoustic probe includes an acoustic transducer having acoustic transducer elements arranged in a one-dimensional array; and a variably-refracting acoustic lens coupled to the acoustic transducer. The variably-refracting acoustic lens has a pair of electrodes configured to adjust the focus of the variably-refracting acoustic lens in response to a selected voltage applied across the electrodes. In one embodiment, the variably-refracting acoustic lens includes a cavity, first and second fluid media disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.Type: GrantFiled: April 27, 2007Date of Patent: June 7, 2011Assignee: Koninklijke Philips Electronics N.V.Inventors: Christopher S. Hall, Chien Ting Chin, Jan Frederik Suijver, Bernardus Hendrikus Wilhelmus Hendriks, Stein Kuiper
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Publication number: 20110125080Abstract: Described is a method for the delivery of a therapeutic agent to a mammal, particularly a human person, comprising (i) the administration of ultrasound particles that undergo a physical change when subjected to ultrasound; (ii) the administration of the therapeutic agent in an ultrasound dosage form allowing release of the therapeutic agent to be affected by the application of ultrasound, (iii) the application of ultrasound so as to affect a physical change in at least some of the ultrasound particles, and (iv) the application of ultrasound so as to stimulate release of the therapeutic agent. According to the invention the ultrasound particles are subjected to detection of their acoustic responses via echoes and/or emissions. The information thus obtained is processed and the processed information is used to adapt or adjust the ultrasound-mediated delivery of the therapeutic agent.Type: ApplicationFiled: June 9, 2009Publication date: May 26, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: William Tao Shi, Chien Ting Chin, Christopher S. Hall, Balasundara Raju, Marcel Rene Bohmer
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Publication number: 20100268072Abstract: A therapeutic ultrasound tracking system (10) includes a first and second plurality of tracking elements ((14, 16, 18),(20,22,24)), a tracking generator (26), and a system controller (28). The first plurality of tracking elements (14, 16, 18) is disposed in a first position and orientation with respect to each another and with respect to an energy emission surface (30) of a therapeutic ultrasound probe (12). The second plurality of tracking elements (20,22,24) is adapted to be coupled to a patient (42) in a second position and orientation with respect to each other and with respect to a target region of the patient which is to receive a therapeutic treatment. The tracking generator (26) emits tracking energy for use in connection with the first and second plurality of tracking elements.Type: ApplicationFiled: November 13, 2008Publication date: October 21, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Christopher Stephen Hall, Chien Ting Chin, Balasundara I. Raju, William Tao Shi, Guy Shechter
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Publication number: 20100087735Abstract: An acoustic probe (100, 300) includes an acoustic transducer (15, 444), and a plurality of variably-refracting acoustic lens elements (10, 210a, 210b, 442) coupled to the acoustic transducer. Each variably-refracting acoustic lens element has at least a pair of electrodes (150, 160) adapted to adjust at least one characteristic of the variably-refracting acoustic lens element in response to a selected voltage applied across the electrodes. In one embodiment, each variably-refracting acoustic lens element includes a cavity, first and second fluid media (141, 142) disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.Type: ApplicationFiled: April 30, 2008Publication date: April 8, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Christopher Stephen Hall, Chien Ting Chin, Jan Frederik Suijver, Bernardus Hendrikus Wilhelmus Hendriks, Stein Kuiper
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Publication number: 20100069754Abstract: An apparatus for application of three-dimensional ultrasound imaging and therapy comprising a two-dimensional ultrasound imaging array of transducer elements having an image signal transmitter and receiver that forms, steers and selectively focuses ultrasound beams to a three-dimensional moving or stationary spatial volume; one or more two-dimensional ultrasound therapy arrays of transducer elements, each array having a therapy signal transmitter that forms, steers and selectively focuses and delivers ultrasound therapy to the volume; wherein the location of the array of imaging and therapy transducer elements are known relative to one another; and a controller that controls the image transmitter and receiver to provide three-dimensional images of the volume and simultaneously independently controls each of the one or more therapy transmitters to deliver therapy to the volume.Type: ApplicationFiled: November 6, 2007Publication date: March 18, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Balasundara Raju, Christopher Hall, Chien Ting Chin, William T. Shi
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Publication number: 20090122639Abstract: An acoustic probe (100) includes an acoustic transducer (20) including a plurality of acoustic transducer elements arranged in a one-dimensional array; and a variably- refracting acoustic lens (10) coupled to the acoustic transducer. The variably-refracting acoustic lens has at least a pair of electrodes (150, 160) adapted to adjust the focus of the variably-refracting acoustic lens in response to a selected voltage applied across the electrodes. In one embodiment, the variably-refracting acoustic lens includes a cavity, first and second fluid media (141, 142) disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.Type: ApplicationFiled: April 27, 2007Publication date: May 14, 2009Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Christopher Hall, Chien Ting Chin, Jan Frederik Suijver, Bernardus Hendrikus Wilhelmus Hendriks, Stein Kuiper
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Publication number: 20080208059Abstract: Method and system for ultrasound imaging of body tissue in which a focused ultrasound (FUS) transducer (20) is oriented relative to the body such that ultrasonic waves generated by the FUS transducer (20) are directed toward the tissue being imaged. The FUS transducer (20) is operated to cause the formation of microbubbles (28) in the tissue and an ultrasound image of the tissue with the microbubbles (28) is acquired. Phase aberration in the acquired ultrasound image may be corrected, if necessary, using each microbubble (28) as a point source or point-like scatterer. Microbubble (28) formation can therefore be obtained in a non-invasive manner since FUS-induced microbubble (28) formation does not require the insertion of interventional tools into the body.Type: ApplicationFiled: March 2, 2006Publication date: August 28, 2008Applicant: Koninklijke Philips Electronics, N.V.Inventors: Christopher Hall, Shunmugavelu Sokka, David Louis Marie Savery, Chien Ting Chin