Abstract: A high performance and integrated nosocomial infection control surveillance and detection system includes a patient database having a patient information, a clinical database having a patient clinical information, a nosocomial infection surveillance model with capability to detect suspected cases, an infection monitoring dashboard presenting an integrated view of a patient information and infection conditions in the clinical database for each patient. The patient database, clinical database, nosocomial infection surveillance model and the infection monitoring dashboard are built in different network servers or a network server to meet the optimum efficiency for a user to conduct infection control and early detection of infected cases through his/her account.