Abstract: A protection guard for vehicle handlebar, which is mounted on a handlebar, includes a fixing arm having an arm body mounted on the handlebar, an arm-to-bracket conjunction portion formed on another end opposite to the handlebar; an adjusting bracket having a bracket body formed of “L” shape, a bracket-to-arm conjunction portion formed on an end of the bracket body, at least two thread holes formed on the bracket-to-arm conjunction portion, a bracket-to-cover joining portion formed on another end, the arm-to-bracket conjunction portion of the fixing arm is threaded to one of the thread holes; and a cover having a cover body, a cover-to-bracket joining portion formed on the cover body and connected to the bracket-to-cover joining portion of the adjusting bracket; thereby, when the adjusting bracket turned around or moved to change the position of the thread hole relative to the arm-to-bracket conjunction portion of the fixing arm, the cover then having variety locating position relative to the handlebar.