Patents by Inventor Chih-An Lin
Chih-An Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240415973Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.Type: ApplicationFiled: August 28, 2024Publication date: December 19, 2024Applicant: Aihol CorporationInventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
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Patent number: 12128108Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.Type: GrantFiled: November 2, 2022Date of Patent: October 29, 2024Assignee: Aihol CorporationInventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
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Publication number: 20230080473Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.Type: ApplicationFiled: November 2, 2022Publication date: March 16, 2023Applicant: Aihol CorporationInventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
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Patent number: 11524079Abstract: Disclosed herein is a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. Also disclosed herein are the uses of the hyaluronan conjugate in treating or preventing neurodegenerative diseases.Type: GrantFiled: June 2, 2020Date of Patent: December 13, 2022Assignee: AIHOL CORPORATIONInventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
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Patent number: 11458204Abstract: Disclosed herein is a method for preparing a hyaluronan-drug conjugate. The method uses the ethyl cyano(hydroxyimino)acetate/diisopropylcarbodiimide coupling system in a homogeneous reaction phase, which unexpectedly improves the substitution rate and substitution efficiency of hyaluronan-drug conjugates for various drugs.Type: GrantFiled: December 10, 2020Date of Patent: October 4, 2022Assignee: Aihol CorporationInventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
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Publication number: 20210369852Abstract: Disclosed herein is a method for preparing a hyaluronan-drug conjugate. The method uses the ethyl cyano(hydroxyimino)acetate/diisopropylcarbodiimide coupling system in a homogeneous reaction phase, which unexpectedly improves the substitution rate and substitution efficiency of hyaluronan-drug conjugates for various drugs.Type: ApplicationFiled: December 10, 2020Publication date: December 2, 2021Applicant: Aihol CorporationInventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
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Publication number: 20200376132Abstract: Disclosed herein is a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. Also disclosed herein are the uses of the hyaluronan conjugate in treating or preventing neurodegenerative diseases.Type: ApplicationFiled: June 2, 2020Publication date: December 3, 2020Applicant: Aihol CorporationInventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
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Patent number: 9323155Abstract: A method of lithography patterning includes forming a first resist pattern on a substrate, wherein the first resist pattern including a plurality of openings. A second resist pattern is formed on the substrate and within the plurality of openings of the first resist pattern, wherein the second resist pattern includes at least one opening therein on the substrate. The first resist pattern is removed to uncover the substrate underlying the first resist pattern.Type: GrantFiled: June 3, 2014Date of Patent: April 26, 2016Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Chun-Kuang Chen, Hsiao-Wei Yeh, Chih-An Lin, Chien-Wei Wang, Feng-Cheng Hsu
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Publication number: 20150259804Abstract: The present invention provides chemical-mechanical polishing (CMP) methods for polishing a tungsten containing substrate. The polishing compositions used with the methods of the invention comprise an aqueous carrier, an abrasive, a polyamino compound, a metal ion, a chelating agent, an oxidizing agent, and optionally, an amino acid. The methods of the invention effectively remove tungsten while reducing surface defects such as recesses typically associated with tungsten CMP.Type: ApplicationFiled: March 5, 2015Publication date: September 17, 2015Inventors: Chih-An LIN, Zhan CHEN
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Publication number: 20140272714Abstract: A method of lithography patterning includes forming a first resist pattern on a substrate, wherein the first resist pattern including a plurality of openings. A second resist pattern is formed on the substrate and within the plurality of openings of the first resist pattern, wherein the second resist pattern includes at least one opening therein on the substrate. The first resist pattern is removed to uncover the substrate underlying the first resist pattern.Type: ApplicationFiled: June 3, 2014Publication date: September 18, 2014Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: CHUN-KUANG CHEN, Hsiao-Wei Yeh, Chih-An Lin, Chien-Wei Wang, Feng-Cheng Hsu
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Publication number: 20140174901Abstract: A keyboard button structure includes a flexible board and a key cap. The flexible board includes an hollow-out body, a first support portion, a second support portion, and an extending arm including a conducting contact. The first supporting is connected to the hollow-out body. A first perpendicular distance is formed between the first support portion and the hollow-out body. The second support portion is connected to the first support portion. The extending arm is connected to the second support portion. A second perpendicular distance is formed between the extending arm and the hollow-out body. The key cap is fixed to the first and the second support portions, and is rotatably coupled to the hollow-out body. When the key cap is moved in a direction toward the hollow-out body by an external force, the extending arm is moved in the direction with the key cap.Type: ApplicationFiled: June 6, 2013Publication date: June 26, 2014Inventor: Chih-An Lin
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Patent number: 8741552Abstract: A method of lithography patterning includes forming a first resist pattern on a substrate, wherein the first resist pattern including a plurality of openings. A second resist pattern is formed on the substrate and within the plurality of openings of the first resist pattern, wherein the second resist pattern includes at least one opening therein on the substrate. The first resist pattern is removed to uncover the substrate underlying the first resist pattern.Type: GrantFiled: February 9, 2010Date of Patent: June 3, 2014Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Chun-Kuang Chen, Hsiao-Wei Yeh, Chih-An Lin, Chien-Wei Wang, Feng-Cheng Hsu
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Publication number: 20140103250Abstract: The invention provides a chemical-mechanical polishing composition comprising coated ?-alumina particles, an organic carboxylic acid, and water. The invention also provides a chemical-mechanical polishing composition comprising an abrasive having a negative zeta potential in the polishing composition, an organic carboxylic acid, at least one alkyls disulfonate surfactant, and water, wherein the polishing composition does not further comprise a heterocyclic compound. The abrasive is colloidally stable in the polishing composition. The invention further provides methods of polishing a substrate with the aforesaid polishing compositions.Type: ApplicationFiled: December 18, 2013Publication date: April 17, 2014Inventors: Ji CUI, Steven GRUMBINE, Glenn WHITENER, Chih-An LIN
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Patent number: 8623766Abstract: The invention provides a chemical-mechanical polishing composition comprising coated ?-alumina particles, an organic carboxylic acid, and water. The invention also provides a chemical-mechanical polishing composition comprising an abrasive having a negative zeta potential in the polishing composition, an organic carboxylic acid, at least one alkyldiphenyloxide disulfonate surfactant, and water, wherein the polishing composition does not further comprise a heterocyclic compound. The abrasive is colloidally stable in the polishing composition. The invention further provides methods of polishing a substrate with the aforesaid polishing compositions.Type: GrantFiled: September 20, 2011Date of Patent: January 7, 2014Assignee: Cabot Microelectronics CorporationInventors: Ji Cui, Steven Grumbine, Glenn Whitener, Chih-An Lin
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Publication number: 20130072021Abstract: The invention provides a chemical-mechanical polishing composition comprising coated ?-alumina particles, an organic carboxylic acid, and water. The invention also provides a chemical-mechanical polishing composition comprising an abrasive having a negative zeta potential in the polishing composition, an organic carboxylic acid, at least one alkyldiphenyloxide disulfonate surfactant, and water, wherein the polishing composition does not further comprise a heterocyclic compound. The abrasive is colloidally stable in the polishing composition. The invention further provides methods of polishing a substrate with the aforesaid polishing compositions.Type: ApplicationFiled: September 20, 2011Publication date: March 21, 2013Inventors: Ji Cui, Steven Grumbine, Glenn Whitener, Chih-An Lin
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Patent number: 8158335Abstract: The present invention includes a lithography method comprising forming a first patterned insist layer including at least one opening therein over a substrate. A water-soluble polymer layer is formed over the first patterned resist layer and the substrate, whereby a reaction occurs at the interface of the first patterned resist layer and the water-soluble polymer layer. The non-reacted water-soluble polymer layer is removed. Thereafter, a second patterned resist layer is formed over the substrate, wherein at least one portion of the second patterned resist layer is disposed within the at least one opening of the first patterned resist layer or abuts at least one portion of the first patterned resist layer. The substrate is thereafter etched using the first and second patterned resist layers as a mask.Type: GrantFiled: September 15, 2008Date of Patent: April 17, 2012Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Hsiao-Wei Yeh, Ching-Yu Chang, Jian-Hong Chen, Chih-An Lin
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Publication number: 20100310995Abstract: A method of lithography patterning includes forming a first resist pattern on a substrate, wherein the first resist pattern including a plurality of openings. A second resist pattern is formed on the substrate and within the plurality of openings of the first resist pattern, wherein the second resist pattern includes at least one opening therein on the substrate. The first resist pattern is removed to uncover the substrate underlying the first resist pattern.Type: ApplicationFiled: February 9, 2010Publication date: December 9, 2010Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.Inventors: Chun-Kuang Chen, Hsiao-Wei Yeh, Chih-An Lin, Chien-Wei Wang, Feng-Cheng Hsu
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Publication number: 20100068656Abstract: The present invention includes a lithography method comprising forming a first patterned insist layer including at least one opening therein over a substrate. A water-soluble polymer layer is formed over the first patterned resist layer and the substrate, whereby a reaction occurs at the interface of the first patterned resist layer and the water-soluble polymer layer. The non-reacted water-soluble polymer layer is removed. Thereafter, a second patterned resist layer is formed over the substrate, wherein at least one portion of the second patterned resist layer is disposed within the at least one opening of the first patterned resist layer or abuts at least one portion of the first patterned resist layer. The substrate is thereafter etched using the first and second patterned resist layers as a mask.Type: ApplicationFiled: September 15, 2008Publication date: March 18, 2010Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.Inventors: Hsiao-Wei Yeh, Ching-Yu Chang, Jian-Hong Chen, Chih-An Lin