Patents by Inventor Chih-Chieh Mao

Chih-Chieh Mao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPLICATION AND PHARMACEUTICAL COMPOSITION OF PREACTIVATED AND DISAGGREGATED SHAPE-CHANGED PLATELETS
    Publication number: 20160263157
    Abstract: Preactivated and disaggregated shape-changed platelets, fixed shape-changed platelets, and a pharmaceutical composition thereof are used for treating acute and emergent inflammatory disease in a dosage of 1×106 to 1×108. SC-PLT is a disaggregated and activated platelet, the secretome from platelet activation has been deprived after SC-PLT preparation but their membrane still preserve cell adhesion molecular and integrin glycoprotein (eg. P-selectin, GP1a, and GPIIb etc.). Therefore, SC-PLTs can trap stromal vascularity inflammatory cells from inflammated and damaged place, and the stromal vascularity inflammatory cells are eliminated through the circulatory system to alleviate inflammation. The fixed shape-changed platelets are able to alleviate inflammation and sustainable for longer storage duration.
    Type: Application
    Filed: May 18, 2016
    Publication date: September 15, 2016
    Inventors: Yuan-Ji Day, Li-Man Hung, Shiang-Suo Huang, Hsiang-Ruei Liao, Chiou-Mei Lee, Jiin-Tarng Liou, Fu-Chao Liu, Chih-Chieh Mao, Polung Yang
  • APPLICATION AND PHARMACEUTICAL COMPOSITION OF PREACTIVATED AND DISAGGREGATED SHAPE-CHANGED PLATELETS
    Publication number: 20150366912
    Abstract: Preactivated and disaggregated shape-changed platelets, fixed shape-changed platelets, and a pharmaceutical composition thereof are used for treating acute and emergent inflammatory disease in a dosage of 1×106 to 1×108. Activated platelets release and transfer adhesion factors to the surface of platelet cells, and trap stromal vascularity inflammatory cells from inflammated and damaged place, and the stromal vascularity inflammatory cells are eliminated through the circulatory system to alleviate inflammation. The fixed shape-changed platelets are able to alleviate inflammation and sustainable for longer storage duration.
    Type: Application
    Filed: August 27, 2015
    Publication date: December 24, 2015
    Applicant: Chang Gung Medical Foundation, Linkou Branch
    Inventors: Yuan-Ji Day, Li-Man Hung, Shiang-Suo Huang, Hsiang-Ruei Liao, Chiou-Mei Lee, Jiin-Tarng Liou, Fu-Chao Liu, Chih-Chieh Mao, Polung Yang
  • APPLICATION AND PHARMACEUTICAL COMPOSITION OF PREACTIVATED AND DISAGGREGATED SHAPE-CHANGED PLATELETS
    Publication number: 20150104436
    Abstract: Preactivated and disaggregated shape-changed platelets, fixed shape-changed platelets, and a pharmaceutical composition thereof are used for treating acute and emergent inflammatory disease in a dosage of 1×106 to 1×108. Activated platelets release and transfer adhesion factors to the surface of platelet cells, and trap stromal vascularity inflammatory cells from inflammated and damaged place, and the stromal vascularity inflammatory cells are eliminated through the circulatory system to alleviate inflammation. The fixed shape-changed platelets are able to alleviate inflammation and sustainable for longer storage duration.
    Type: Application
    Filed: October 13, 2013
    Publication date: April 16, 2015
    Applicant: CHANG GUNG MEDICAL FOUNDATION, LINKOU BRANCH
    Inventors: Yuan-Ji Day, Li-Man Hung, Shiang-Suo Huang, Hsiang-Ruei Liao, Chiou-Mei Lee, Jiin-Tarng Liou, Fu-Chao Liu, Chih-Chieh Mao, Polung Yang