Abstract: A wire-guiding structure of a shuttle of a sewing machine is disclosed. One end surface of the shuttle is formed with a wire-receiving hole for supplying wire continuously. A wire for seaming is supplied to an interior of the shuttle from an external larger scale wire-winding and the wire is wound around the wire-winding wheel for outputting. It is unnecessary to update the shuttle so as to increase the finishing efficiency. Furthermore, the end surface of the shuttle is installed with a wire-guiding rod for guiding wire successfully so that the wire can run along a predetermined path efficiently. Thus wire can be supplied successfully. Moreover, a wire-winding wheel is installed in the shuttle so that wire will be easily wound around the wire-winding wheel smoothly. Thus wire is supplied to the sewing machine successfully.