Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: A two-stage gas regulator for liquefied-gas containers includes a lower body and an upper cover with a mediate plate disposed therebetween. The lower body has a plurality of inlet ports respectively in fluid communication with a corresponding liquefied-gas container, a first pressure-reduction chamber selectively in fluid communication with one of the inlet ports under control of a switch, a second pressure-reduction chamber in fluid communication with the first pressure-reduction chamber, and an outlet port in fluid communication with the second pressure-reduction chamber and a gas stove. The mediate plate has a first opening and a second opening respectively in alignment with the first and second pressure-reduction chambers. A first membrane is provided in the first pressure-reduction chamber to cover the first opening, and a second membrane is provided in the second pressure-reduction chamber to cover the second opening and for operating a secondary pressure reduction.