Abstract: The present utility model relates generally to an improved electrode structure, comprising of: an electrode material, and the electrode material has weight percentage of 80-96%; an electrically conductive material, and the electrically conductive material has weight percentage of 2-10%; an adhesive, and the adhesive has a weight percentage of 2-10%; a low toxicity and environmentally friendly solvent, and the low toxicity environmentally friendly solvent has weight percentage of 20-70% in positive electrode material, and 100-150% in negative electrode material; wherein the improved electrode structure was given with treatment of baking temperature of 50-150° C., with process time of 8 to 12 hours.

Abstract: A method of detecting severe disease-associated mutations in an enterovirus 71 (EV-A71), comprising: performing an assay on a test sample containing an EV-A71 genomic RNA, a fragment thereof or an amplicon thereof, or an EV-A71 VP1 protein or fragment thereof to detect one or more severe disease-associated mutations in the EV-A71 genomic RNA, the fragment thereof or the amplicon thereof, or the EV-A71 protein or fragment thereof, wherein the one or more mutations are selected from mutations at positions corresponding to 5? UTR nucleotide positions C580, A707, and C709 in an EV-A71 5? UTR nucleic acid sequence and at residues corresponding to A280 and E145 in an EV-A71 VP1 protein sequence.