Patents by Inventor Chih-Wen Shu

Chih-Wen Shu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated peptide, anti-cancer medicinal composition including the same and method of specifically reducing or inhibiting activities of cancer cells using the same
    Patent number: 11866516
    Abstract: The present invention relates to an isolated peptide, an anti-cancer medicinal composition including the same and a method of specifically reducing or inhibiting activities of cancer cells using the same. The isolated peptide including a TAT basic domain conjugated to a GABARAPL2 H2 domain can specifically reduce or inhibit an activity of cancer cells, thereby being applied to the anti-cancer medicinal composition and the method of specifically reducing or inhibiting activities of cancer cells using the same.
    Type: Grant
    Filed: June 16, 2022
    Date of Patent: January 9, 2024
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: Chih-Wen Shu
  • ISOLATED PEPTIDE, ANTI-CANCER MEDICINAL COMPOSITION INCLUDING THE SAME AND METHOD OF SPECIFICALLY REDUCING OR INHIBITING ACTIVITIES OF CANCER CELLS USING THE SAME
    Publication number: 20220340618
    Abstract: The present invention relates to an isolated peptide, an anti-cancer medicinal composition including the same and a method of specifically reducing or inhibiting activities of cancer cells using the same. The isolated peptide including a TAT basic domain conjugated to a GABARAPL2 H2 domain can specifically reduce or inhibit an activity of cancer cells, thereby being applied to the anti-cancer medicinal composition and the method of specifically reducing or inhibiting activities of cancer cells using the same.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 27, 2022
    Inventor: CHIH-WEN SHU
  • Isolated peptide, anti-cancer medicinal composition including the same and method of specifically reducing or inhibiting activities of cancer cells using the same
    Patent number: 11396529
    Abstract: The present invention relates to an isolated peptide, an anti-cancer medicinal composition including the same and a method of specifically reducing or inhibiting activities of cancer cells using the same. The isolated peptide including a TAT basic domain conjugated to a GABARAPL2 H2 domain can specifically reduce or inhibit an activity of cancer cells, thereby being applied to the anti-cancer medicinal composition and the method of specifically reducing or inhibiting activities of cancer cells using the same.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: July 26, 2022
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventor: Chih-Wen Shu
  • ISOLATED PEPTIDE, ANTI-CANCER MEDICINAL COMPOSITION INCLUDING THE SAME AND METHOD OF SPECIFICALLY REDUCING OR INHIBITING ACTIVITIES OF CANCER CELLS USING THE SAME
    Publication number: 20220144890
    Abstract: The present invention relates to an isolated peptide, an anti-cancer medicinal composition including the same and a method of specifically reducing or inhibiting activities of cancer cells using the same. The isolated peptide including a TAT basic domain conjugated to a GABARAPL2 H2 domain can specifically reduce or inhibit an activity of cancer cells, thereby being applied to the anti-cancer medicinal composition and the method of specifically reducing or inhibiting activities of cancer cells using the same.
    Type: Application
    Filed: November 12, 2020
    Publication date: May 12, 2022
    Inventor: Chih-Wen SHU
  • Method for the treatment of ATG4-related disorders
    Patent number: 10583123
    Abstract: The present invention relates to the area of ATG4-related disorders. More particularly, the present invention relates to a method of treating an ATG4B-related disorder comprising a step of administering a subject with an effective amount of tioconazole. The present invention relates also to a method of increasing a subject's responsiveness to a therapy for a cancer comprising inhibition of ATG4B activity in cells; said method comprises administering the subject with an effective amount of tioconazole. The present invention also relates to a method for enhancing or inducing a response in a cancer cell consisting of cytotoxicity, chemosensitivity or starvation-sensitivity; said method comprises administering a subject with an effective amount of tioconazole to inhibit ATG4B's activity.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: March 10, 2020
    Assignee: National Tsing Hua University
    Inventors: Lee-Wei Yang, Chih-Wen Shu, Pei-Feng Liu, Kun-Lin Tsai
  • METHOD FOR THE TREATMENT OF ATG4-RELATED DISORDERS
    Publication number: 20190183860
    Abstract: The present invention relates to the area of ATG4-related disorders. More particularly, the present invention relates to a method of treating an ATG4B-related disorder comprising a step of administering a subject with an effective amount of tioconazole. The present invention relates also to a method of increasing a subject's responsiveness to a therapy for a cancer comprising inhibition of ATG4B activity in cells; said method comprises administering the subject with an effective amount of tioconazole. The present invention also relates to a method for enhancing or inducing a response in a cancer cell consisting of cytotoxicity, chemosensitivity or starvation-sensitivity; said method comprises administering a subject with an effective amount of tioconazole to inhibit ATG4B's activity.
    Type: Application
    Filed: December 15, 2017
    Publication date: June 20, 2019
    Inventors: Lee-Wei Yang, Chih-Wen Shu, Pei-Feng Liu, Kun-Lin Tsai