Patents by Inventor Chih Y. Ho

Chih Y. Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fatty acid leukotriene synthesis inhibitors
    Patent number: 4908384
    Abstract: Fatty acid compounds of the formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, A, Y and k are as defined herein are novel and useful in the treatment of allergic and inflammatory disorders.
    Type: Grant
    Filed: August 29, 1986
    Date of Patent: March 13, 1990
    Assignee: McNeilab, Inc.
    Inventors: Chih Y. Ho, Richard J. Mohrbacher
  • Method for the treatment of LHRH diseases and conditions
    Patent number: 4678784
    Abstract: Fused tetracyclic benzodiazepines of the formula (I): ##STR1## where R.sup.1 is a cyclic amine such as 1-piperazine and R.sup.2 is H or a substituent as defined herein are useful as LHRH antagonizing agents. Also, methods for their synthesis, intermediates used in such synthesis, methods for use as medicaments and pharmaceutical compositions are described.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: July 7, 1987
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho
  • 1-amino-or nitro-benzyl)indoles useful as intermediates
    Patent number: 4587349
    Abstract: Compounds of the present invention are of the formula (III): ##STR1## wherein R.sup.2 is a substituent as disclosed, R is alkyl and Y is NO.sub.2 or NH.sub.2. The invention compounds are useful as intermediates for tetracyclic benzodiazepines which may be used in treating hypertension.
    Type: Grant
    Filed: March 18, 1985
    Date of Patent: May 6, 1986
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho
  • Amidine benzodiazepines, methods for their use and intermediates
    Patent number: 4587244
    Abstract: Fused tetracyclic benzodiazepines of the formula (I): ##STR1## where R.sup.1 is a cyclic amine such as 1-piperazine and R.sup.2 is H or a substituent as defined herein are useful as antiovulatory and contragestational agents. Also, methods for their synthesis, intermediates used in such synthesis, methods for use as medicaments and pharmaceutical compositions are described.
    Type: Grant
    Filed: April 10, 1985
    Date of Patent: May 6, 1986
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho
  • Aryl fatty acid leukotriene synthesis inhibitors
    Patent number: 4564476
    Abstract: Aryl fatty acid compounds of the formula (I) ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, X, and Y are as defined herein are novel and useful in the treatment of allergic and inflammatory disorders.
    Type: Grant
    Filed: October 29, 1984
    Date of Patent: January 14, 1986
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho
  • Amidine benzodiazepines, methods for their use and intermediates
    Patent number: 4547497
    Abstract: Fused tetracyclic benzodiazepines of the formula (I): ##STR1## where R.sup.1 is an acyclic amine or cyclic amine such as 1-piperidine, 4-morpholine or 1-piperazine and R.sup.2 is H or a substituent as defined herein as useful as antiallergins. Also, methods for their synthesis, intermediate used in such synthesis, methods for use as medicaments and pharmaceutical compositions.
    Type: Grant
    Filed: April 11, 1984
    Date of Patent: October 15, 1985
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho
  • 6H-indolo[2,1-c][1,4]benzodiazepines and 12-oxo derivatives useful as antihypertensives
    Patent number: 4529724
    Abstract: Compounds of the present invention are of the formula (I): ##STR1## wherein X is oxygen or two hydrogens, R.sup.1 is a variety of substituents or hydrogen and R.sup.2 is hydrogen, alkoxy, alkyl, CF.sub.3, halogen, NO.sub.2, OH or dialkylamino. The compounds are useful as blood pressure lowering agents and may be used in the treatment of hypertension. Also, part of the invention are pharmaceutical compositions and uses and intermediates for compounds of formula (I).
    Type: Grant
    Filed: October 11, 1983
    Date of Patent: July 16, 1985
    Assignee: McNeilab, Inc.
    Inventor: Chih Y. Ho