Patents by Inventor Chihiro Hama, legal representative

Chihiro Hama, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Host, transformant and method for producing the transformant and method for producing O-glycosylated heterologous protein
    Patent number: 8318454
    Abstract: The object is to provide a transformant which can produce a heterologous protein having a structurally controlled O-linked sugar chain having an O-Man-Gal disaccharide structure, a method for producing the transformant by using Schizosaccharomyces pombe as the host, and provide a host for producing the transformant and a method for producing an O-glycosylated heterologous protein. An Schizosaccharomyces pombe host having no omh1 gene or an inactivated omh1 gene in its chromosomes for producing an O-glycosylated heterologous protein having an O-linked sugar chain having an O-Man-Gal disaccharide structure by expression of the heterologous protein by a genetic engineering technique and subsequent glycosylation of the expressed heterologous protein. A transformant from the host, a method for producing the transformant and a method for producing an O-glycosylated heterologous protein by using the transformant.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: November 27, 2012
    Assignee: Asahi Glass Company, Limited
    Inventors: Kaoru Takegawa, Yuko Hama, Chihiro Hama, legal representative, Hideki Tohda