Patents by Inventor Chi Hung N'Guyen

Chi Hung N'Guyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of isoquinolones for preparing drugs, novel isoquinolones and method for synthesising same
    Patent number: 8883763
    Abstract: The use of isoquinolones for preparing drugs, including novel isoquinolones as well as their synthesis method. In particular, isoquinolone derivatives used in the treatment of pathological angiogenesis, and more particularly of cancer.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: November 11, 2014
    Assignees: Universite Joseph Fourier, Centre National de la Recherche Scientifique, Institut Curie
    Inventors: Andrei Popov, Aurélie Juhem, Jean-Claude Florent, Chi-Hung N'Guyen
  • Condensed pyridine derivatives useful as potent inhibitors of the protein kinase CK2
    Patent number: 8686144
    Abstract: The invention relates to the use of specific compounds of formula (I) and their pharmaceutically-acceptable salts: (Formula 1) (I) as a new family of protein kinase CK2 inhibitors; the invention also relates to the use of compounds of formula (I) for the preparation of pharmaceutical compositions for the prevention and/or treatment of disorders and/or diseases chosen amongst cancers; autoimmune and inflammatory diseases; infectious diseases; diabetes angiogenesis related disorders; retinopathies and cardiac hypertrophy.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: April 1, 2014
    Assignees: Commissariat a l'Energie Atomique et aux Energie Alternative, Institut National de la Sante et de la Recherche Medicale (INSERM), Institut Curie, Centre National de la Recherche Scientifique
    Inventors: Claude Cochet, Renaud Prudent, Virginie Moucadel, Chi-Hung N'guyen
  • AMINO-SUBSTITUTED-ALKYLOXY-BENZO[E]PYRIDO[4,3-B]INDOLE DERIVATIVES AS NEW POTENT KINASE INHIBITORS
    Publication number: 20140073637
    Abstract: The present invention relates to a new class of benzo[e]pyrido-indole, the amino-substituted-alkyloxy-benzo[e]pyrido[4,3-b]indole derivatives, having a particular kinase inhibition profile and useful as a therapeutic agent, in particular an anti-tumoral agent.
    Type: Application
    Filed: May 30, 2012
    Publication date: March 13, 2014
    Applicants: INSTITUT CURIE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Chi-Hung N'Guyen, Annie Molla, Ly-Thuy-Tram Le
  • USE OF ISOQUINOLONES FOR PREPARING DRUGS, NOVEL ISOQUINOLONES AND METHOD FOR SYNTHESISING SAME
    Publication number: 20130096083
    Abstract: The use of isoquinolones for preparing drugs, including novel isoquinolones as well as their synthesis method. In particular, isoquinolone derivatives used in the treatment of pathological angiogenesis, and more particularly of cancer.
    Type: Application
    Filed: March 1, 2011
    Publication date: April 18, 2013
    Applicants: UNIVERSITE JOSEPH FOURIER, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Andrei Popov, Aurelie Juhem, Jean-Claude Florent, Chi-Hung N'Guyen
  • CONDENSED PYRIDINE DERIVATIVES USEFUL AS POTENT INHIBITORS OF THE PROTEIN KINASE CK2
    Publication number: 20120178759
    Abstract: The invention relates to the use of specific compounds of formula (I) and their pharmaceutically-acceptable salts: (Formula 1) (I) as a new family of protein kinase CK2 inhibitors; the invention also relates to the use of compounds of formula (I) for the preparation of pharmaceutical compositions for the prevention and/or treatment of disorders and/or diseases chosen Camongst cancers; autoimmune and inflammatory diseases; infectious diseases; diabetes angiogenesis related disorders; retinopathies and cardiac hypertrophy.
    Type: Application
    Filed: July 28, 2010
    Publication date: July 12, 2012
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, INSTITUT NAT DE LA SAN ET DE LA RECH MED (INSERM)
    Inventors: Claude Cochet, Renaud Prudent, Virginie Moucadel, Chi-Hung N'guyen
  • Pyridinone and pyridinethione derivatives having HIV inhibiting properties
    Patent number: 7115608
    Abstract: The present invention is concerned among others with compounds of formula (1), the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein Q is halo, C1-6 alkyl or C2-6 alkenyl; X is (a-2) with q and r being O and Z being O, S or SO; R1 is aryl; R2 is selected from formyl; C1-6alkyloxycarbonylalkyl; Het2; Het2C1-6alkyl, C1-6alkylthio; C1-6alkyl optionally substituted with one or two substituents each independently selected from hydroxy, and halo; R3 is selected from formyl; C1-6alkyl optionally substituted with one or two C1-6alkyloxy; R4 is hydrogen, with HTV inhibiting properties
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: October 3, 2006
    Assignees: Centre National de la Recherche Schentifique, Institute Curie
    Inventors: Jérôme Guillemont, Abdellah Benjahad, Dominique Mabire, Chi Hung N'Guyen, David Grierson, Claude Monneret, Emile Bisagni, Gérard Sanz, Laurence Decrane
  • Pyridinone and pyridinethione derivatives having hiv inhibiting properties
    Publication number: 20040229847
    Abstract: The present invention is concerned among others with compounds of formula (I), the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein Q is halo, C1-6 alkyl or C2-6 alkenyl; X is (a-2) with q and r being O and Z being O, S or SO; R1 is aryl; R2 is selected from formyl; C1-6alkyloxycarbonylalkyl; Het2; Het2C1-6alkyl, C1-6alkylthio; C1-6alkyl optionally substituted with one or two substituents each independently selected from hydroxy, and halo; R3 is selected from formyl; C1-6alkyl optionally substituted with one or two C1-6alkyloxy; R1 is hydrogen, with HTV inhibiting properties.
    Type: Application
    Filed: March 18, 2003
    Publication date: November 18, 2004
    Inventors: Jerome Guillemont, Abdellah Benjahad, Dominique Mabire, Chi Hung N'guyen, David Gierson, Claude Monneret, Emile Bisagni, Gerard Sanz, Laurence Decrane