Abstract: An endoscope system includes: a light source configured to emit white light having wavelength distribution of white color; an optical element configured to block at least light emitted from the light source, the at least light having wavelength band corresponding to a light absorption band with a highest peak from among light absorption bands of a medicinal substance used in phototherapy; an imaging element configured to perform imaging based on a light component which has passed through the optical element; and an image processor configured to process imaging signal obtained as a result of imaging performed by the imaging element, and generate an image.

Abstract: An endoscope system according to the present invention includes: an illumination light source that emits illumination light for illuminating an object; a therapeutic light source that emits therapeutic light for causing a photoreactive reagent accumulated in a treatment target site to react; a guide light source that emits guide light having a wavelength shorter than a wavelength band of the therapeutic light source; an imager that captures an optical image, the imager including an optical filter that cuts light in the wavelength band of the therapeutic light and transmits a part of white light, the guide light, and fluorescence emitted by the reagent; a controller that controls emission timings of the illumination light source, the therapeutic light source, and the guide light source; and an image processor that generates an image on the basis of an optical image obtained by light emitted from the illumination light source, the therapeutic light source, and the guide light source, in which the controller cau

Abstract: A phototherapy device includes: a treatment light emitter configured to emit treatment light for causing a reaction of a drug; a first imager configured to obtain a tissue structure image which is formed using narrow band light applied onto an application position of the treatment light; a second imager configured to obtain a fluorescence image which is formed using excitation light applied onto the application position of the treatment light; a boundary region calculator configured to refer to the tissue structure image to determine a boundary region in which a tissue structure has changed; a fluorescence intensity variation calculator configured to calculate magnitude of variation in fluorescence intensity of the boundary region; and a display image generator configured to generate a display image to be used for displaying the magnitude of variation of the fluorescence intensity.

Abstract: Provided is a spectroscopic analysis apparatus including: an optical probe; and a spectroscopic analysis portion to which the optical probe is attached. The optical probe includes an optical fiber that guides illumination light coming from a light source and signal light coming from an observation target and an optical member that is disposed at least at a distal end of the optical fiber. The spectroscopic analysis portion includes an information separation portion that generates wavelength dependent characteristics by optically dispersing the signal light and that separates, from information about the signal light, information about first return light returning from the optical member and information about second return light returning from the optical fiber, a problem determining portion that determines a problem occurring at the optical probe based on the separated first return light and second return light, and a notification portion that notifies information about the determined problem.

Abstract: Provided is a spectroscopic analysis apparatus including: an optical probe; and a spectroscopic analysis portion to which the optical probe is attached. The optical probe includes an optical fiber that guides illumination light coming from a light source and signal light coming from an observation target and an optical member that is disposed at least at a distal end of the optical fiber. The spectroscopic analysis portion includes an information separation portion that generates wavelength dependent characteristics by optically dispersing the signal light and that separates, from information about the signal light, information about first return light returning from the optical member and information about second return light returning from the optical fiber, a problem determining portion that determines a problem occurring at the optical probe based on the separated first return light and second return light, and a notification portion that notifies information about the determined problem.

Abstract: An organic compound analyzer is provided which is capable of highly accurately determining a denaturation feature point on which a minute structural change of an organic compound is reflected. The organic compound analyzer includes an actual measured data storage section, an evaluation criterion vector setting section, a score calculation section, and a change feature point determination section. The actual measured data storage section is configured to store in pairs a plurality of actual measured spectra obtained through measurement of a sample containing an organic compound under a plurality of different external stimulus conditions, and external stimulus conditions under which spectra are respectively measured. The evaluation criterion vector setting section is configured to set a loading that indicates weighting to individual wavenumbers at which the spectra are measured.

Abstract: An organic compound analyzer is provided which is capable of highly accurately determining a denaturation feature point on which a minute structural change of an organic compound is reflected. The organic compound analyzer includes an actual measured data storage section, an evaluation criterion vector setting section, a score calculation section, and a change feature point determination section. The actual measured data storage section is configured to store in pairs a plurality of actual measured spectra obtained through measurement of a sample containing an organic compound under a plurality of different external stimulus conditions, and external stimulus conditions under which spectra are respectively measured. The evaluation criterion vector setting section is configured to set a loading that indicates weighting to individual wavenumbers at which the spectra are measured.

Abstract: Raman spectra of protein solutions having a plurality of concentrations are acquired. An index, which changes according to interaction between protein molecules, is calculated based on a predetermined peak included in the Raman spectra. A threshold of concentration at which protein can be denatured is specified based on change in the index against change in concentration. The threshold is compared with a concentration of the protein solution required as medicine such as antibody drug, and whether the protein solution is suitable as medicine or not is determined. When the concentration required as medicine is equal to or higher than the threshold, for example, it is judged that the protein solution is not suitable as medicine. When the protein solution is not suitable as medicine, analysis can be repeated by changing a condition of the protein solution.