Abstract: A transdermal patch includes a backing film, an adhesive matrix and a release liner. The adhesive matrix contains two active pharmaceutical ingredients, pramipexole and rasagiline. The transdermal patch is to be applied on skins for 7 days to deliver pramipexole and rasagiline for the treatment of Parkinson's disease.

Abstract: A cosmetic composition to prevent and/or ameliorate skin aging and applications thereof are provided in the present disclosure and the cosmetic composition comprises cyclic phosphatidic acid and citrus flavonoids which is hesperidin and/or hesperetin wherein the preventing and/or ameliorating skin aging include, without limitation, promoting moisture retention of stratum corneum, promoting skin elasticity, increasing presence or elasticity of collagens and elastins in fibroblasts, increasing transfers of fibroblasts, promoting anti-oxidation, increasing generation of hyaluronic acid, alleviating wrinkles and skin textures, moderating melanin, reducing skin oil and preventing transepidermal water losses.

Abstract: A cosmetic composition to prevent and/or ameliorate skin aging and applications thereof are provided in the present disclosure and the cosmetic composition comprises cyclic phosphatidic acid and citrus flavonoids which is hesperidin and/or hesperetin wherein the preventing and/or ameliorating skin aging include, without limitation, promoting moisture retention of stratum corneum, promoting skin elasticity, increasing presence or elasticity of collagens and elastins in fibroblasts, increasing transfers of fibroblasts, promoting anti-oxidation, increasing generation of hyaluronic acid, alleviating wrinkles and skin textures, moderating melanin, reducing skin oil and preventing transepidermal water losses.

Abstract: The present disclosure provides dosage forms designed to deliver active pharmaceutical ingredients (APIs) in a controlled release manner. For instance, the present disclosure includes dosage forms with adequate time of onset of action and reduced lag times in the fed state. Such dosage forms find use in a variety of conditions where a rapid onset of action is desired followed by an extended release phase for the active agent, for example in the treatment of ADHD, pain or anxiety. In some cases, the dosage form includes a drug composition including a pharmacologically active agent, a barrier layer covering at least a portion of the drug composition, and a drug layer covering at least a portion of the barrier layer, wherein the drug layer includes the pharmacologically active agent. Related methods of making and administering the disclosed dosage forms are also provided.

Abstract: The present invention provides multi-layer capsules and manufacture methods thereof. Different materials are added in sequence into a capsule to form a multi-layer capsule without diffusion and/or interaction between layers.

Abstract: The present invention provides multi-layer capsules and manufacture methods thereof Different materials are added in sequence into a capsule to form a multi-layer capsule without diffusion and/or interaction between layers.

Abstract: In a light-emitting diode light bar of a light-emitting device, a first lead and a second lead are juxtaposed with a distance. A light-emitting diode crystal has a first electrode and a second electrode. Then, the first electrode is electrically fixed to the first lead. The second electrode is electrically connected to the second lead via a metallic lead. A light-transmitting body is used to package the light-emitting diode crystal and the metallic lead. Finally, via a hot pressing process, an insulating layer covers the first lead and the second lead. In this way, a light-emitting diode light bar is formed.

Abstract: The present invention generally relates to transdermal drug delivery systems. More particularly, the present invention provides compositions and transdermal drug delivery systems for the treatment and/or relief of symptoms associated with carpal tunnel syndrome or tendonitis.

Abstract: In a light-emitting diode light bar of a light-emitting device, a first lead and a second lead are juxtaposed with a distance. A light-emitting diode crystal has a first electrode and a second electrode. Then, the first electrode is electrically fixed to the first lead. The second electrode is electrically connected to the second lead via a metallic lead. A light-transmitting body is used to package the light-emitting diode crystal and the metallic lead. Finally, via a hot pressing process, an insulating layer covers the first lead and the second lead. In this way, a light-emitting diode light bar is formed.

Abstract: In a full-cover light-emitting diode light bar that can withstand a large bending deformation, a first lead and a second lead are juxtaposed with a distance. An insulating layer having a slot is formed on the first lead and the second lead via a hot pressing process. A crystal-receiving section of the first lead is displayed in the slot, and a connecting section of the second lead is displayed in the slot. A light-emitting diode crystal has a first electrode and a second electrode. Then, the light-emitting diode crystal is disposed in the slot with the first electrode being electrically fixed to the crystal-receiving section. The second electrode of the light-emitting diode crystal is electrically connected to the connecting section via a metallic lead. A light-transmitting body is used to seal the slot. Via the above process, a full-cover light-emitting diode light bar is formed.

Abstract: In a light-emitting diode light bar of a light-emitting device, a first lead and a second lead are juxtaposed with a distance. A light-emitting diode crystal has a first electrode and a second electrode. Then, the first electrode is electrically fixed to the first lead. The second electrode is electrically connected to the second lead via a metallic lead. A light-transmitting body is used to package the light-emitting diode crystal and the metallic lead. Finally, via a hot pressing process, an insulating layer covers the first lead and the second lead. In this way, a light-emitting diode light bar is formed.

Abstract: A flat cable covering means for generating different impedances includes a plurality of cores, an insulating body and a first metallic covering layer. The cores are arranged at an interval respectively. The insulating body covers an outer surface of the cores. The first metallic covering layer is provided to correspond to a portion of cores and partially covers one side of the insulating body with the impedance of the cores in an area covered by the first metallic covering layer smaller than that of the cores in an area not covered by the first metallic covering layer. Via this arrangement, in order to correspond to the need of impedances of different devices in the electronic apparatus, the different impedances can be made integrally in the same flat cable. In this way, not only the manufacturing and assembling processes can be simplified, but also the management and layout of lines are simple and convenient.

Abstract: The present invention is directed to compositions and methods for the transdermal delivery of a pharmaceutically active compound. In some embodiments, the addition of inert pharmaceutical ingredients in place of a portion of adhesive in a transdermal patch formulation increases the rate of skin permeation of a pharmaceutical compound.

Abstract: The present invention is directed to compositions for the sustained delivery of an antibiotic, for example vancomycin, to achieve desirable release profiles. This application is also directed to methods of using the compositions and processes for manufacturing the compositions.

Abstract: A flat cable covering means for generating different impedances includes a plurality of cores, an insulating body and a first metallic covering layer. The cores are arranged at an interval respectively. The insulating body covers an outer surface of the cores. The first metallic covering layer is provided to correspond to a portion of cores and partially covers one side of the insulating body with the impedance of the cores in an area covered by the first metallic covering layer smaller than that of the cores in an area not covered by the first metallic covering layer. Via this arrangement, in order to correspond to the need of impedances of different devices in the electronic apparatus, the different impedances can be made integrally in the same flat cable. In this way, not only the manufacturing and assembling processes can be simplified, but also the management and layout of lines are simple and convenient.

Abstract: A flat cable connector includes an insulating base. Both ends of the insulating base have a protruding buckling end respectively. The buckling ends on both ends and a plate body of the insulating base form an accommodating space for accommodating the flat cable therein. The insulating base is provided thereon with a plurality of penetrating holes for penetrating the plate body. Both surfaces of the insulating base are connected with an upper conductive cover and a lower conductive cover respectively. The upper conductive cover and the lower conductive cover are provided with a plurality of fixing terminals. After the upper conductive cover is connected with the insulating base, the fixing terminals of the upper conductive cover abut against the flat cable.

Abstract: A flat cable connector includes an insulating base. Both ends of the insulating base have a protruding buckling end respectively. The buckling ends on both ends and a plate body of the insulating base form an accommodating space for accommodating the flat cable therein. The insulating base is provided thereon with a plurality of penetrating holes for penetrating the plate body. Both surfaces of the insulating base are connected with an upper conductive cover and a lower conductive cover respectively. The upper conductive cover and the lower conductive cover are provided with a plurality of fixing terminals. After the upper conductive cover is connected with the insulating base, the fixing terminals of the upper conductive cover abut against the flat cable.

Abstract: A flat cable includes a plurality of flat cores arranged at an interval, an insulating layer covering integrally each core, and an adhesive sheet. Both surfaces of the insulating layer are provided with a plurality of grooves to correspond to the cores respectively. The distal end of each core extends beyond the insulating layer and each has a connecting portion. Each connecting portion has two flat surfaces. One of the flat surfaces is used for electrical connection, and the other is adhered to the adhesive sheet. The adhesive sheet is adhered from the distal end of each connecting portion to a portion of the insulating layer. Further, an external surface of the adhesive sheet is colored.

Abstract: The application relates to the controlled release of a hypnotic agent with extended release profiles. The pharmaceutical composition and processes for manufacturing, and methods of using the controlled release formulation are provided.

Abstract: The invention relates to the composition of a novel formulation of eprosartan with enhanced bioavailability. The formulation comprises of eprosartan or a salt, solvate, or hydrate thereof, a solubilizer, and an emulsifier. A process for manufacturing, and methods of using the formulation to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure are also provided.