Patents by Inventor Chin-Chin Teo

Chin-Chin Teo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents
    Patent number: 5459139
    Abstract: The synthesis and the biological evaluation of a series of basic ethers of 2-benzyl-3-arylbenzofurans as antitumor agents is described. These compounds bind significantly to the antiestrogen-binding sites but only poorly to the estrogen receptor sites and are cytotoxic to tumor cells. Some of these compounds also significantly inhibited de novo cholesterol biosynthesis in an estrogen receptor negative lymphoma cell line rich in antiestrogen-binding sites.
    Type: Grant
    Filed: June 1, 1994
    Date of Patent: October 17, 1995
    Assignee: National University of Singapore
    Inventors: Keng-Yeow Sim, Oi-Lian Kon, Chin-Chin Teo, Siu-Choon Ng, Srikanth Natarajan
  • 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents
    Patent number: 5354861
    Abstract: The synthesis and the biological evaluation of a series of basic ethers of 2-benzyl-3-arylbenzofurans as antitumor agents is described. These compounds bind significantly to the antiestrogen-binding sites but only poorly to the estrogen receptor sites and are cytotoxic to tumor cells. Some of these compounds also significantly inhibited de novo cholesterol biosynthesis in an estrogen receptor negative lymphoma cell line rich in antiestrogen-binding sites.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: October 11, 1994
    Assignee: National University of Singapore
    Inventors: Keng-Yeow Sim, Oi-Lian Kon, Chin-Chin Teo, Siu-Choon Ng, Srikanth Natarajan