Abstract: Orthodontic brackets are disclosed. An orthodontic bracket is formed such that the body and mesh portions are formed integrally in one piece, and the tooth-side mounting surface includes bonding elements that have an undercut angle to the mounting surface. The bonding elements can further include geometry to facilitate the spreading of bonding material. In some aspects, the bracket can also comprise elements for wire-mounting and aligner tray interaction. A system and methods of treatment are further disclosed. The bracket can be customized for an individual patient.

Abstract: A novel nanocomposite including hydroxyapatite-gelatin bioceramic material and dopamine, wherein the dopamine undergoes an oxidative self-polymerization reaction to form the novel nanocomposite. The nanocomposite displays superior mechanical strength, elasticity, biocompatibility and forming capabilities and is targeted for bone repairs and template-assisted tissue engineering applications. In addition, improved aminosilica-based hydroxyapatite-gelatin bioceramic bioceramics are disclosed.

Abstract: A formable bioceramic including hydroxyapatite nanocrystals, gelatin, and sol-gel-containing material is described. Also described is a process for making and using the bioceramic. The formable bioceramic displays superior mechanical strength, elasticity, biocompatibility and forming capabilities and is targeted for bone repairs and template-assisted tissue engineering applications.

Abstract: A biomimetic nanocomposite including hydroxyapatite nanocrystals, gelatin, and polymer, wherein the biomimetic nanocomposite is crosslinked is described. Also described is a process for making the nanocomposite. Additionally, a method for using the nanocomposite, and articles formed from the nanocomposite are also described.