Abstract: In an embodiment, a method of forming a structure includes forming a first transistor and a second transistor over a first substrate; forming a front-side interconnect structure over the first transistor and the second transistor; etching at least a backside of the first substrate to expose the first transistor and the second transistor; forming a first backside via electrically connected to the first transistor; forming a second backside via electrically connected to the second transistor; depositing a dielectric layer over the first backside via and the second backside via; forming a first conductive line in the dielectric layer, the first conductive line being a power rail electrically connected to the first transistor through the first backside via; and forming a second conductive line in the dielectric layer, the second conductive line being a signal line electrically connected to the second transistor through the second backside via.

Abstract: Disclosed is a (D331Y) PLA2G6 knockin mouse, which shows similar clinical symptoms to those of patients suffering from Parkinson's disease (PD), and begins to display early-onset cell death of dopaminergic neurons in its substantia nigra (SN), synucleinopathy, and tau pathology at the age of about 6 months, wherein the dopaminergic neurons exhibit mitochondrial structural abnormality and dysfunction. Treatment of the (D331Y) PLA2G6 knockin mouse with L-Dopa shows a good response. The (D331Y) PLA2G6 knockin mouse can be used as a platform for developing a medicament and method for treating PD.

Abstract: A light-emitting diode device is described, which includes a luminous body and a colloid. The luminous body has a light-emitting surface and a bottom surface on opposite sides. The luminous body has a first length, a first width and a beam angle. The colloid covers the luminous body. The colloid includes a first surface and a second surface on opposite sides. The second surface has a second length and a second width. The colloid has a refractive index. A distance between the light-emitting surface of the luminous body and the second surface of the colloid is smaller than a first value and greater than a second value. The first value < the ? ? second ? ? width - the ? ? first ? ? width 2 · cot ? ? ? . The second value < the ? ? second ? ? width - the ? ? first ? ? width 2 · cot ? ? v . The sin ?=1/the refractive index of the colloid, and the ? is a full width at half maximum of the beam angle.

Abstract: The present invention discloses a labeled molecule for prognosing the tumor grade of head and neck cancer and a method for the same, wherein a 78-kDA glucose regulated protein (GRP78) is adopted as a labeled molecule of head and neck cancer. GRP78 is much more overexpressed in head and neck cancer cells than in non-cancer cells. GRP78 also has relation with tumor size, tumor depth and tumor metastasis. Therefore, the present invention uses GRP78 overexpression as a reference for tumor grading of head and neck cancer.

Abstract: The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5?-AAGGATGGTTAATGATGCTGAGAA-3? [SEQ. ID NO: 1] complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.

Abstract: The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5?-AAGGATGGTTAATGATGCTGAGAA-3? complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.

Abstract: The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5?-AAGGATGGTTAATGATGCTGAGAA-3? complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.

Abstract: The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5?-AAGGATGGTTAATGATGCTGAGAA-3? complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.

Abstract: The present invention discloses a specific GRP78 expression-inhibition RNAi sequence, a medicine thereof and a method thereof, wherein an RNAi sequence 5?-AAGGATGGTTAATGATGCTGAGAA-3? complementary to GRP78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer.

Abstract: The present invention discloses a labeled molecule for prognosing the tumor grade of head neck cancer and a method for the same, wherein a 78-kDA glucose regulated protein (GRP78) is adopted as a labeled molecule of head neck cancer. GRP78 is much more overexpressed in head neck cancer cells than in non-cancer cells. GRP78 also has relation with tumor size, tumor depth and tumor metastasis. Therefore, the present invention uses GRP78 overexpression as a reference for tumor grading of head neck cancer.

Abstract: The present invention relates generally to “The structure of fuel complete Combustion Acceleration for Automotive Vehicles” which contains a rubber vesicant and led metal sheet (or led type metal sheet), which the rubber vesicant is formed by mixing and allotting with proper ration of rubber and metal oxide material which contains far infrared ray. Therefore, the rubber vesicant has function of electromagnetic wave with far infrared ray. When the rubber vesicant is wrapped up with the outer part of the tube which supplies oil and air in a automotive vehicle, it can catalyze the oil and air molecule passing through the tube to a rearrangement in order by the heating arising from the engine, meanwhile it will dash against the molecule into tiny ones so as to promote the gas to burn thoroughly.