Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.

Abstract: An optical material includes a substrate, and an optical unit formed on the substrate and including a base layer of a base polymer, an optical layer of a polymer, and a complex layer disposed between the base layer and the optical layer. The complex layer is formed by the following steps: contacting one side of the base layer with a solution containing a monomeric compound of the polymer such that the monomeric compound penetrates into the base layer so as to form a penetrated region in the base layer and that a polymerizable layer of the monomeric compound of the polymer is formed on the penetrated region; and polymerizing the monomeric compound of the polymerizable layer and the monomeric compound in the penetrated region so as to form the optical layer and the complex layer, respectively. A method for making the optical material is also disclosed.

Abstract: A footwear has a novel shoe upper. The shoe upper is soft and wear-resisting. The making of the shoe upper is simple and the cost is low.

Abstract: A shoe upper is non-yellowed by using a film. The film is covered on a leather. The film has the function of discoloration and has a low density.