Patents by Inventor Ching-Chow CHEN

Ching-Chow CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,5,N-TRIHYDROXY-ALKANAMIDE OR 3,5,N-TRIHYDROXY-6-ALKENAMIDE DERIVATIVE ALONE OR IN COMBINATION WITH CHEMOTHERAPEUTIC AGENT FOR TREATING CANCER
    Publication number: 20170273921
    Abstract: The present invention provides a novel method for treating cancer that comprises administering a compound represented by formula (I) and/or a chemotherapeutic agent to a subject. The present invention further provides a novel kit that comprises a compound represented by formula (I) and a chemotherapeutic agent for treating cancer.
    Type: Application
    Filed: August 14, 2015
    Publication date: September 28, 2017
    Inventor: Ching-Chow Chen
  • 3,5,N-trihydroxy-alkanamide and derivatives: method for making same and use thereof
    Patent number: 9353061
    Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR). Also provided are methods of using the compounds and pharmaceutical compositions for inhibiting the activity of HDACs and HMGR, treating diseases associated with HDACs or HMGR (e.g., cancer, hypercholesterolemia, an acute or chronic inflammatory disease, autoimmune disease, allergic disease, pathogen infection, neurodegenerative disease, and a disease associated with oxidative stress), or inhibiting drug resistance of cancer cells.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: May 31, 2016
    Assignees: ACADEMIA SINICA, NATIONAL TAIWAN UNIVERSITY
    Inventors: Jung-Hsin Lin, Jim-Min Fang, Ting-Rong Chern, Jhih-Bin Chen, Ching-Chow Chen, Tzu-Tang Wei
  • Dual action inhibitors against histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme a reductase
    Patent number: 9115116
    Abstract: Disclosed herein are novel compounds of formula (I), and uses thereof. The compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR). Also provided are methods of using the compounds of Formula (I) for inhibiting the activity of HDACs and HMGR, treating diseases associated with HDACs or HMGR (e.g.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: August 25, 2015
    Assignees: Academia Sinica, National Taiwan University
    Inventors: Jung-Hsin Lin, Ching-Chow Chen, Jim-Min Fang, Jhih-Bin Chen, Ting-Rong Chern, Tzu-Tang Wei
  • 3,5,N-TRIHYDROXY-ALKANAMIDE AND DERIVATIVES: METHOD FOR MAKING SAME AND USE THEREOF
    Publication number: 20150148360
    Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR). Also provided are methods of using the compounds and pharmaceutical compositions for inhibiting the activity of HDACs and HMGR, treating diseases associated with HDACs or HMGR (e.g., cancer, hypercholesterolemia, an acute or chronic inflammatory disease, autoimmune disease, allergic disease, pathogen infection, neurodegenerative disease, and a disease associated with oxidative stress), or inhibiting drug resistance of cancer cells.
    Type: Application
    Filed: July 19, 2013
    Publication date: May 28, 2015
    Inventors: Jung-Hsin Lin, Jim-Min Fang, Ting-Rong Chen, Jhih-Bin Chen, Ching-Chow Chen, Tzu-Tang Wei
  • DUAL ACTION INHIBITORS AGAINST HISTONE DEACETYLASES AND 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE
    Publication number: 20140206645
    Abstract: Disclosed herein are novel compounds of formula (I), and uses thereof. The compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR). Also provided are methods of using the compounds of Formula (I) for inhibiting the activity of HDACs and HMGR, treating diseases associated with HDACs or HMGR (e.g.
    Type: Application
    Filed: January 21, 2014
    Publication date: July 24, 2014
    Applicants: National Taiwan University, Academia Sinica
    Inventors: Jung-Hsin LIN, Ching-Chow CHEN, Jim-Min FANG, Jhih-Bin CHEN, Ting-Rong CHERN, Tzu-Tang WEI