Patents by Inventor Ching Hsuan

Ching Hsuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9321889
    Abstract: A copolymer of DCPD-containing benzoxazine (DCPDBz) and cyanate ester resin forms a low-dielectric thermosetting polymeric material for making electronic components. A method of manufacturing the copolymer is also introduced. The method includes allowing DCPD-phenol oligomer, aniline, and paraformaldehyde to react at 110° C. for 6-12 hours before being extracted and baked to obtain DCPDBz; and mixing cyanate ester and the DCPDBz at 150° C.; heating the mixture up to 220° C.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: April 26, 2016
    Assignee: NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Wen-Chiung Su, Ching-Hsuan Lin, Sheng-Chen Liao, Yu-Wei Chou
  • Patent number: 9265844
    Abstract: Provided herein are polypeptides that are selectively cleaved by cathepsin E. Also provided are methods of detecting cathepsin E. The methods comprise contacting cathepsin E with the polypeptides provided herein and detecting fluorescence. Further provided are methods of diagnosing cancer or pre-cancerous conditions in a subject. Also provided herein is a multilayered nanoparticle or a composition comprising the multilayer nanoparticle, wherein the multilayered nanoparticle comprises a negatively charged nanoparticle core or capsule coated with alternating positive and negative layers. Optionally, the positive layer comprises a positively charged protease degradable polypeptide. Optionally, the negative layer comprises a negatively charged therapeutic agent or a therapeutic agent and a means for providing the agent with a negative charge. For example, optionally, the therapeutic agent is linked to a negatively charged polymer.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: February 23, 2016
    Assignees: THE METHODIST HOSPITAL SYSTEM, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Ching-Hsuan Tung, Wael R. Abd-Elgaliel, Craig D. Logsdon, Zobeida Cruz-Monserrate
  • Patent number: 9217061
    Abstract: A series of novel phosphorus-containing compounds having the formula: is provided in which R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof, as well as a polymer of formula (PI), and preparation process and use thereof are also provided.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: December 22, 2015
    Assignees: Chang Chun Plastics Co., Ltd., National Chung Hsing University
    Inventors: Ching-Hsuan Lin, Tsung Li Lin, Yu-Ting Fang, Kuen-Yuan Hwang, An-Pang Tu
  • Publication number: 20150218316
    Abstract: A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Inventors: Ching-Hsuan LIN, Tsung Li LIN, Yu-Ting FANG, Kuen-Yuan HWANG, An-Pang TU
  • Patent number: 8929070
    Abstract: An expansion apparatus suitable for an electronic apparatus is provided. The expansion apparatus includes a base, a supporter and an airflow guiding structure. The base has a first fan disposed therein. The supporter is pivoted to the base along a rotating axis and has a cooling channel. The cooling channel has a first port and a second port opposite to the first port. When the electronic apparatus is assembled to the supporter, the second port of the cooling channel faces to the electronic apparatus. The airflow guiding structure is disposed between the supporter and the base movably. When the supporter is pivoted relative to the base to an expanded state, an active airflow generated by the first fan is guided by the airflow guiding structure to pass through the base and the electronic apparatus. An electronic equipment including the expansion apparatus is also provided.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 6, 2015
    Assignee: Compal Electronics, Inc.
    Inventors: Shih-Huei Liu, Chun-Jen Shih, Ching-Hsuan Wang, Pan-Jen Chen, Po-Han Chen
  • Patent number: 8843521
    Abstract: A method for analyzing data utilizing a weighted suffix tree includes receiving at least one original data sequence. An original data sequence ID is assigned to the original data sequence, and the original data sequence includes an original datums. A weighted suffix tree is constructed according to the original datums of the original data sequence. The weighted suffix tree includes several nodes, and each node includes a weight set which is formed by the original data sequence ID. Group information for classifying the original datums into several groups is received. The nodes of the weighted suffix tree belonging to a same group are merged according to the group information. Data is analyzed according to the weighted suffix tree after being merged.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: September 23, 2014
    Assignee: National Central University
    Inventors: Meng-Feng Tsai, Min-Feng Wang, Cheng-Hsien Tang, Bo-Ru Song, Ching-Hsuan Shen, Hsin-Fu Su, Chi-Sheng Huang
  • Patent number: 8841388
    Abstract: The present invention provides novel phosphinated compounds of monofunctional, bifunctional, multifunctional phenols represented by the following formulae and their derivatives, and preparation methods thereof:
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: September 23, 2014
    Assignee: National Chung Hsing University
    Inventors: Ching-Hsuan Lin, Yu-Wei Tian
  • Patent number: 8822723
    Abstract: A series of curing agents are provided. The curing agents are multi-functional and phosphorus-containing. The curing agents have excellent processability to be used as an epoxy resin curing agent. The curing agents can be cured to obtain a phosphorus-containing epoxy thermoset with flame retardancy characteristic. The epoxy thermosets are very fit for circuit board substrate having high glass transition temperature; semiconductor packaging material; and related materials.
    Type: Grant
    Filed: May 7, 2011
    Date of Patent: September 2, 2014
    Assignee: Chung-Shan Institute of Science and Technology, Armaments, Bureau, Ministry of National Defense
    Inventors: Wen-Chiung Su, Ching-Hsuan Lin, Hung-Tse Lin
  • Patent number: 8791229
    Abstract: A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: July 29, 2014
    Assignees: Chang Chun Plastics Co., Ltd., National Chung Hsing University
    Inventors: Ching-Hsuan Lin, Tsung Li Lin, Yu-Ting Fang, Kuen-Yuan Hwang, An-Pang Tu
  • Patent number: 8703882
    Abstract: Phosphorus-containing benzoxazine-based bisphenols and derivatives thereof are disclosed. The phosphorus-containing benzoxazine-based bisphenols are prepared by reacting DOPO with benzoxazine to form the phosphorus-containing benzoxazine-based bisphenols. The phosphorus-containing benzoxazine-based bisphenols can further to form advanced epoxy resins. The advanced epoxy resins can further be cured to form flame retardant epoxy thermosets.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: April 22, 2014
    Assignee: National Chunghsing University
    Inventors: Ching-Hsuan Lin, Hung-Tse Lin, Sheng Lung Chang, Yu-Ming Hu
  • Publication number: 20140088283
    Abstract: A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
    Type: Application
    Filed: October 31, 2013
    Publication date: March 27, 2014
    Applicants: National Chung Hsing University, Chang Chun Plastics Co., Ltd.
    Inventors: Ching-Hsuan LIN, Tsung Li Lin, Yu-Ting Fang, Kuen-Yuan Hwang, An-Pang Tu
  • Patent number: 8648164
    Abstract: Disclosed is a method for making a low-k, flame-retardant, bi-functional benzoxazine. The method includes the steps of dissolving phosphoric diamine with various functional groups, phenolic adamantane and paraformaldehyde in a solvent at 72° C. to 88° C. for 7 to 9 hours, and cooling and introducing the solution in n-hexane to separate the low-k, flame-retardant, phosphoric, bi-functional benzoxazine.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: February 11, 2014
    Assignee: Chung-Shan Institute of Science and Technology, Armaments, Bureau, Ministry of National Defense
    Inventors: Wen-Chiung Su, Ching-Hsuan Lin, Hung-Tse Lin, Feng-Jen Wang
  • Patent number: 8598307
    Abstract: A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 3, 2013
    Assignees: Chang Chun Plastics Co., Ltd., National Chung Hsing University
    Inventors: Ching-Hsuan Lin, Tsung Li Lin, Yu-Ting Fang, Kuen-Yuan Hwang, An-Pang Tu
  • Patent number: 8552426
    Abstract: A composite dielectric material doped with rare earth metal oxide and a manufacturing method thereof are provided. The composite dielectric material is doped with nano-crystalline rare metal oxide which is embedded in silicon dioxide glass matrix, and the composite dielectric material of the nano-crystalline rare metal oxide and the silicon dioxide glass matrix is synthesized by the manufacturing method using sol-gel route. The dielectric value of the glass composite dielectric material is greater than that of pure rare metal oxide or that of silicon dioxide. In presence of magnetic field, the dielectric value of the composite dielectric material is substantially enhanced compared with that of the composite dielectric material at zero field.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: October 8, 2013
    Assignee: National Sun Yat-Sen University
    Inventors: Hung-Duen Yang, Sudip Mukherjee, Ching-Hsuan Chen
  • Patent number: 8551811
    Abstract: A composite dielectric material doped with rare earth metal oxide and a manufacturing method thereof are provided. The composite dielectric material is doped with nano-crystalline rare metal oxide which is embedded in silicon dioxide glass matrix, and the composite dielectric material of the nano-crystalline rare metal oxide and the silicon dioxide glass matrix is synthesized by the manufacturing method using sol-gel route. The dielectric value of the glass composite dielectric material is greater than that of pure rare metal oxide or that of silicon dioxide. In presence of magnetic field, the dielectric value of the composite dielectric material is substantially enhanced compared with that of the composite dielectric material at zero field.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: October 8, 2013
    Assignee: National Sun Yat-Sen University
    Inventors: Hung-Duen Yang, Sudip Mukherjee, Ching-Hsuan Chen
  • Patent number: 8546798
    Abstract: A composite dielectric material doped with rare earth metal oxide and a manufacturing method thereof are provided. The composite dielectric material is doped with nano-crystalline rare metal oxide which is embedded in silicon dioxide glass matrix, and the composite dielectric material of the nano-crystalline rare metal oxide and the silicon dioxide glass matrix is synthesized by the manufacturing method using sol-gel route. The dielectric value of the glass composite dielectric material is greater than that of pure rare metal oxide or that of silicon dioxide. In presence of magnetic field, the dielectric value of the composite dielectric material is substantially enhanced compared with that of the composite dielectric material at zero field.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: October 1, 2013
    Assignee: National Sun Yat-Sen University
    Inventors: Hung-duen Yang, Sudip Mukherjee, Ching-hsuan Chen
  • Publication number: 20130251640
    Abstract: Provided herein are polypeptides that are selectively cleaved by cathepsin E. Also provided are methods of detecting cathepsin E. The methods comprise contacting cathepsin E with the polypeptides provided herein and detecting fluorescence. Further provided are methods of diagnosing cancer or pre-cancerous conditions in a subject. Also provided herein is a multilayered nanoparticle or a composition comprising the multilayer nanoparticle, wherein the multilayered nanoparticle comprises a negatively charged nanoparticle core or capsule coated with alternating positive and negative layers. Optionally, the positive layer comprises a positively charged protease degradable polypeptide. Optionally, the negative layer comprises a negatively charged therapeutic agent or a therapeutic agent and a means for providing the agent with a negative charge. For example, optionally, the therapeutic agent is linked to a negatively charged polymer.
    Type: Application
    Filed: December 1, 2011
    Publication date: September 26, 2013
    Applicant: THE METHODIST HOSPITAL SYSTEM
    Inventors: Ching-Hsuan Tung, Wael R. Abd-Elgaliel
  • Patent number: 8486373
    Abstract: An intramolecularly-quenched, near infrared fluorescence probe that emits substantial fluorescence only after interaction with a target tissue (i.e., activation) is disclosed. The probe includes a polymeric backbone and a plurality of near infrared fluorochromes covalently linked to the backbone at fluorescence-quenching interaction-permissive positions separable by enzymatic cleavage at fluorescence activation sites. The probe optionally includes protective chains or fluorochrome spacers, or both. Also disclosed are methods of using the intramolecularly-quenched, near infrared fluorescence probes for in vivo optical imaging.
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: July 16, 2013
    Assignee: The General Hospital Corporation
    Inventors: Ralph Weissleder, Ching-Hsuan Tung, Umar Mahmood, Lee Josephson, Alexei Bogdanov
  • Publication number: 20130179393
    Abstract: A method for analyzing data utilizing a weighted suffix tree includes receiving at least one original data sequence. An original data sequence ID is assigned to the original data sequence, and the original data sequence includes an original datums. A weighted suffix tree is constructed according to the original datums of the original data sequence. The weighted suffix tree includes several nodes, and each node includes a weight set which is formed by the original data sequence ID. Group information for classifying the original datums into several groups is received. The nodes of the weighted suffix tree belonging to a same group are merged according to the group information. Data is analyzed according to the weighted suffix tree after being merged.
    Type: Application
    Filed: July 6, 2012
    Publication date: July 11, 2013
    Applicant: NATIONAL CENTRAL UNIVERSITY
    Inventors: Meng-Feng TSAI, Min-Feng WANG, Cheng-Hsien TANG, Bo-Ru SONG, Ching-Hsuan SHEN, Hsin-Fu SU, Chi-Sheng HUANG
  • Publication number: 20130155615
    Abstract: An expansion apparatus suitable for an electronic apparatus is provided. The expansion apparatus includes a base, a supporter and an airflow guiding structure. The base has a first fan disposed therein. The supporter is pivoted to the base along a rotating axis and has a cooling channel. The cooling channel has a first port and a second port opposite to the first port. When the electronic apparatus is assembled to the supporter, the second port of the cooling channel faces to the electronic apparatus. The airflow guiding structure is disposed between the supporter and the base movably. When the supporter is pivoted relative to the base to an expanded state, an active airflow generated by the first fan is guided by the airflow guiding structure to pass through the base and the electronic apparatus. An electronic equipment including the expansion apparatus is also provided.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 20, 2013
    Inventors: Shih-Huei Liu, Chun-Jen Shih, Ching-Hsuan Wang, Pan-Jen Chen, Po-Han Chen