Patents by Inventor Ching-Huai Ko
Ching-Huai Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180143181Abstract: An in vitro method for screening a testing compound to evaluate its potential as a liver drug is provided. The method includes applying the testing compound to cells of an isolated human liver tumor cell line, named as ITRI-H16, measuring a cell viability of the cells and determining the effect of the testing compound on the cells by calculating a half maximal inhibitory concentration (IC50) of the testing compound.Type: ApplicationFiled: January 3, 2018Publication date: May 24, 2018Applicant: Industrial Technology Research InstituteInventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Chung Wang, Hsiang-Wen Tseng
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Publication number: 20180142214Abstract: An in vitro method for screening a testing compound to evaluate its potential as a liver drug of the disclosure is provided. The method includes applying the testing compound to cells of an isolated human liver tumor cell line, named as ITRI-H28, measuring a cell viability of the cells and determining the effect of the testing compound on the cells by calculating a half maximal inhibitory concentration (IC50) of the testing compound.Type: ApplicationFiled: January 3, 2018Publication date: May 24, 2018Applicant: Industrial Technology Research InstituteInventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Min Liu, Hsiang-Wen Tseng
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Patent number: 9827182Abstract: The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest.Type: GrantFiled: December 1, 2015Date of Patent: November 28, 2017Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Shan Chang Chueh, Ching Huai Ko, Nien Tzu Chou, Cheng Ming Chuong, Chih Chiang Chen
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Patent number: 9827181Abstract: The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest.Type: GrantFiled: March 10, 2014Date of Patent: November 28, 2017Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Shan Chang Chueh, Ching Huai Ko, Nien Tzu Chou, Cheng Ming Chuong, Chih Chiang Chen
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Patent number: 9682062Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: GrantFiled: December 18, 2013Date of Patent: June 20, 2017Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng Pan, Hsin-Jan Yao, Mei-Wei Lin, I-Huang Lu, Hsin-Chieh Wu, Hsiang-Wen Tseng, Ching-Huai Ko, Chun-Chung Wang, Zong-Keng Kuo, Shyh-Horng Lin, Yi-Cheng Cheng, Tien-Soung Tong
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Patent number: 9597370Abstract: The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest.Type: GrantFiled: December 1, 2015Date of Patent: March 21, 2017Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Shan Chang Chueh, Ching Huai Ko, Nien Tzu Chou, Cheng Ming Chuong, Chih Chiang Chen
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Patent number: 9402876Abstract: The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest.Type: GrantFiled: September 23, 2014Date of Patent: August 2, 2016Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, UNIVERSITY OF CALIFORNIAInventors: Shan Chang Chueh, Ching Huai Ko, Nien Tzu Chou, Cheng Ming Chuong, Chih Chiang Chen
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Publication number: 20160081903Abstract: The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest.Type: ApplicationFiled: December 1, 2015Publication date: March 24, 2016Inventors: SHAN CHANG CHUEH, CHING HUAI KO, NIEN TZU CHOU, CHENG MING CHUONG, CHIH CHIANG CHEN
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Publication number: 20160074470Abstract: The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest.Type: ApplicationFiled: December 1, 2015Publication date: March 17, 2016Inventors: SHAN CHANG CHUEH, CHING HUAI KO, NIEN TZU CHOU, CHENG MING CHUONG, CHIH CHIANG CHEN
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Publication number: 20160008319Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: ApplicationFiled: September 24, 2015Publication date: January 14, 2016Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
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Publication number: 20150159141Abstract: An isolated human liver tumor cell line is provided, which was named as ITRI-H28 and deposited in the Food Industry Research and Development Institute with the accession number BCRC960457 on Dec. 14, 2012. A method of an agent screening is also provided. The method includes providing the isolated human liver tumor cell line ITRI-H28 and adding an interest compound into the ITRI-H28 cell line to determine an effect on the ITRI-H28 cell line.Type: ApplicationFiled: October 9, 2014Publication date: June 11, 2015Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Min Liu, Hsiang-Wen Tseng
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Publication number: 20150160195Abstract: An isolated human liver tumor cell line is provided and is named as ITRI-H16, and which was deposited in the Food Industry Research and Development Institute with the accession number BCRC960432 on Nov. 7, 2011. A method of an agent screening is also provided. The method includes providing the isolated human liver tumor cell line ITRI-H16 and treating an interest compound to the ITRI-H16 cell line to determine an effect of the interesting compound on the ITRI-H16 cell line.Type: ApplicationFiled: October 13, 2014Publication date: June 11, 2015Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Chung Wang, Hsiang-Wen Tseng
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Publication number: 20150148300Abstract: The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest.Type: ApplicationFiled: September 23, 2014Publication date: May 28, 2015Inventors: SHAN CHANG CHUEH, CHING HUAI KO, NIEN TZU CHOU, CHENG MING CHUONG, CHIH CHIANG CHEN
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Publication number: 20140364378Abstract: The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest.Type: ApplicationFiled: March 10, 2014Publication date: December 11, 2014Inventors: SHAN CHANG CHUEH, CHING HUAI KO, NIEN TZU CHOU, CHENG MING CHUONG, CHIH CHIANG CHEN
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Publication number: 20140170250Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: ApplicationFiled: December 18, 2013Publication date: June 19, 2014Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
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Patent number: 7714146Abstract: The invention is related to novel azulene-oxindole compounds having formula (I) shown below, wherein one of R1, R2 and R3 represents a moiety of formula (II), each of A1 and A2 independently is nitrogen, oxygen or sulfur, each of the others of R1, R2, R3, R1, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 is as recited in the specification. The novel compound potentially inhibits multiple kinases and thus can be used to treat some disease like cancer or inflammatory.Type: GrantFiled: October 31, 2007Date of Patent: May 11, 2010Assignee: Industrial Technology Research InstituteInventors: On Lee, Chrong-Shiong Hwang, Chih-Hung Chen, Yuan-Jang Tsai, Chih-Peng Liu, Ching-Huai Ko, Hsin-Hsin Shen, Ling-Mei Wang, Kuei-Tai Lai, Ying-Chu Shih, Ting-Shou Chen, Yen-Chun Chen, Lain-Tze Lee
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Publication number: 20080125590Abstract: An azulene compound is provided. The azulene compound has formula (I) shown below. Each variable in formula (I) is defined in the specification. One of R1, R2, R3, R4, R5, R6, R7, and R8 in formula (I) is a moiety of formula (II). The compound can be used to treat cancer.Type: ApplicationFiled: October 31, 2007Publication date: May 29, 2008Applicant: Industrial Technology Research InstituteInventors: On Lee, Chrong-Shiong Hwang, Chih-Hung Chen, Yuan-Jang Tsai, Chih Peng Liu, Ching-Huai Ko, Hsin-Hsin Shen, Ling-Mei Wang, Kuei-Tai Lai, Ying-Chu Shih, Ting-Shou Chen, Yen-Chun Chen, Lain-Tze Lee