Patents by Inventor Ching-I Wu

Ching-I Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for manufacturing stereoselective preparation of 4-BMA using a chiral auxiliary and chiral auxiliary
    Publication number: 20110144326
    Abstract: The present invention relates to a process for preparing (3R,4S)-3-[[[R]-1?-t-butyldimethylsilyloxy]ethyl]-4-[(R)-1?-carboxyethyl]-2-azetidinone (beta-methylazetidin-2-one; 4-BMA), a key intermediate for the synthesis of carbapenem and penem antibiotics. Specifically, the present invention relates to a process comprising first, the preparation of a chiral auxiliary from cheap L-Phenylalaninol, and then the preparation of 4-BMA in high yield and high selectivity, under industrially mild condition.
    Type: Application
    Filed: December 10, 2009
    Publication date: June 16, 2011
    Inventors: Wei-Hong Tseng, Shiuan-Ting Chuang, Zun-Yuan Hung, Ching-I Wu