Patents by Inventor Ching SHANG

Ching SHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11981711
    Abstract: Provided herein are compositions, systems, kits, and methods for treating nervous system injuries caused by trauma or neurodegeneration or aging in a subject by administering a CSPG or SOCS3 reduction peptide (CRP and SRP respectively), or a nucleic acid sequence encoding the CRP or SRP, wherein both the CRP and SRP comprise a cell membrane penetrating domain, and a lysosome targeting domain, and the CRP further comprises a chondroitin sulfate proteoglycan (CSPG) binding domain, and the SRP further comprises a suppressor of cytokine signaling-3 (SOCS3) binding domain.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: May 14, 2024
    Assignee: The Cleveland Clinic Foundation
    Inventors: Yu-Shang Lee, Ching-Yi Lin
  • Patent number: 11961891
    Abstract: A semiconductor device includes a channel component of a transistor and a gate component disposed over the channel component. The gate component includes: a dielectric layer, a first work function metal layer disposed over the dielectric layer, a fill-metal layer disposed over the first work function metal layer, and a second work function metal layer disposed over the fill-metal layer.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: April 16, 2024
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD
    Inventors: Ru-Shang Hsiao, Ching-Hwanq Su, Pohan Kung, Ying Hsin Lu, I-Shan Huang
  • Patent number: 11949000
    Abstract: A method includes forming a dummy gate stack over a fin protruding from a semiconductor substrate, forming gate spacers on sidewalls of the dummy gate stack, forming source/features over portions of the fin, forming a gate trench between the gate spacers, which includes trimming top portions of the gate spacers to form a funnel-like opening in the gate trench, and forming a metal gate structure in the gate trench. A semiconductor structure includes a fin protruding from a substrate, a metal gate structure disposed over the fin, gate spacers disposed on sidewalls of the metal gate structure, where a top surface of each gate spacer is angled toward the semiconductor fin, a dielectric layer disposed over the top surface of each gate spacer, and a conductive feature disposed between the gate spacers to contact the metal gate structure, where sidewalls of the conductive feature contact the dielectric layer.
    Type: Grant
    Filed: July 27, 2022
    Date of Patent: April 2, 2024
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Ru-Shang Hsiao, Ching-Hwanq Su, Pin Chia Su, Ying Hsin Lu, I-Shan Huang
  • Patent number: 10149783
    Abstract: This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patentcy of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: December 11, 2018
    Assignee: Somnics, Inc.
    Inventors: Chung-Chu Chen, Ching Shang, Marina Sirota, Zhen Yao
  • Patent number: 9387117
    Abstract: This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patency of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: July 12, 2016
    Assignee: Somnics, Inc.
    Inventors: Chung-Chu Chen, Ching Shang, Marina Sirota, Zhen Yao
  • Publication number: 20160166425
    Abstract: This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patentcy of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere.
    Type: Application
    Filed: February 22, 2016
    Publication date: June 16, 2016
    Inventors: Chung-Chu Chen, Ching Shang, Marina Sirota, Zhen Yao
  • Patent number: 8040102
    Abstract: A solar-powered LED street light that can immediately report its power data. The disclosed LED street light has a solar cell, a switch power supply unit, and a power cable data communicating unit. The mains power cable of the LED street light connects to the switch power supply unit for providing it with DC power. The solar cell has a solar board, a battery and a charge controller. The charge controller can also provide the LED street light with DC power. The charge controller has a power data digital output interface for connecting with the power cable data communicating unit, outputting the power data of the solar cell to the power cable data communicating unit. Through the mains power cable, the status of solar cell of each LED lamp is monitored.
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: October 18, 2011
    Assignee: Acbel Polytech Inc.
    Inventors: Ching-Shang Kao, Wei-Liang Lin
  • Publication number: 20110073119
    Abstract: This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patentcy of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere.
    Type: Application
    Filed: September 27, 2010
    Publication date: March 31, 2011
    Applicant: SOMNICS, INC.
    Inventors: Chung-Chu CHEN, Ching SHANG, Marina SIROTA, Zhen YAO
  • Patent number: 7825274
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: November 2, 2010
    Assignee: Chung Shan Institute of Science and Technology
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Patent number: 7741505
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: June 22, 2010
    Assignee: Chung Shan Institute of Science and Technology
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Publication number: 20090303703
    Abstract: A solar-powered LED street light that can immediately report its power data. The disclosed LED street light has a solar cell, a switch power supply unit, and a power cable data communicating unit. The mains power cable of the LED street light connects to the switch power supply unit for providing it with DC power. The solar cell has a solar board, a battery and a charge controller. The charge controller can also provide the LED street light with DC power. The charge controller has a power data digital output interface for connecting with the power cable data communicating unit, outputting the power data of the solar cell to the power cable data communicating unit. Through the mains power cable, the status of solar cell of each LED lamp is monitored.
    Type: Application
    Filed: January 27, 2009
    Publication date: December 10, 2009
    Inventors: Ching-Shang Kao, Wei-Liang Lin
  • Patent number: 7465819
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: December 16, 2008
    Assignee: Chung Shan Institute of Science and Technology
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Publication number: 20080287701
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Application
    Filed: June 18, 2008
    Publication date: November 20, 2008
    Applicant: CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Publication number: 20080255381
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Application
    Filed: June 18, 2008
    Publication date: October 16, 2008
    Applicant: CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Publication number: 20070173659
    Abstract: A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is First, 10-chloro-9,10-dihydro-9-oxa-10-phosphaphenanthrene (CDOP) is prepared by using 2-phenylphenol, and then is esterified to synthesize 6-methoxy-(6H)-dibenz[c,e][1,2]oxa-phosphorin (MDOP). Next, acid chloride compounds are added for performing the Arbuzov reaction to synthesize bisbiphenylacylphosphine oxide. CDOP is hydrolyzed to be derived into 9,10-dihydro-9-oxa-10-phosphaphen-anthrene-10-oxide (DOPO), and then DOPO reacts with arylaldehyde to form secondary alcohol. Therefore, bisbiphenylacylphosphine oxide is prepared by using secondary alcohol under oxidation. Also, under a coupling reaction, DOPO reacts with the acid chloride compounds by using a Lewis acid as a catalyst to prepare bisbiphenylacylphosphine oxide.
    Type: Application
    Filed: January 24, 2006
    Publication date: July 26, 2007
    Inventors: Wen-Chiung Su, Chang-Chih Lin, Ching-Shang Sheng
  • Patent number: D731419
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: June 9, 2015
    Assignee: ACBEL POLYTECH INC.
    Inventors: Ching-Shang Kao, Chiu-Lih Chang, Sheng-Yung Lai, Wei-Qiang Li