Abstract: The compound 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD) has been produced by bioconversion of ricinoleic acid by Pseudomonas aeruginosa PR3. TOD and derivatives thereof are useful for controlling biological organisms, such as fungi and insects.

Abstract: A strain of Pseudomonas Sp. bacterium (NRRL B-18602) has been discovered which is capable of converting oleic acid to the novel compound, 7,10-dihydroxy-8-octadecenoic acid (DOD). The production of DOD is unique in that it involves a hydroxylation at two positions and a rearrangement of the double bond of the substrate molecule. The new multifunctional, long-chain aliphatic acid has potential utility as a plasticizer and as a source of intermediates in the synthesis of specialty chemicals.

Abstract: A novel compound, 12,13,17-trihydroxy-9(Z)-octadecenoic acid (THOA) was produced from linoleic acid by microbial transformation at 25% yield. The newly isolated microbial strain catalyzing this transformation was identified as Clavibacter sp. ALA2 (Accession No. NRRL B-21660). THOA and its derivatives have application as antifungal agents.

Abstract: Process and equipment for advancing the oxidation state of a gaseous oxidizable organic substrate through contact with oxygen and a solid state biocatalyst. The process comprises passing through a stationary catalytic bed comprising moist, resting cells exhibiting oxygenase activity, a gaseous, oxidizable organic substrate and a gaseous source of oxygen, until the oxidative state of at least a portion of said substrate is increased, while maintaining the relative humidity in said bed at such a level that said cells remain moist and viable, and while maintaining the temperature in the vapor state. The process uses an oxygenase enzyme as a catalyst, for the incorporation of molecular oxygen directly into a specific organic molecule. The invention is of particular interest for the conversion of propylene to propylene oxide, and similar reactions that are catalyzed by mono-oxygenase enzymes.